Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.42 |
| ▸ | IDH1 | O75874 | 13/20 | 0.41 |
| ▸ | IDH2 | P48735 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | BCL6 | P41182 | 1/20 | 0.33 |
| ▸ | MBOAT4 | Q96T53 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6182361 | 0.77 | PRMT6 (0.41) | PRMT6IDH1IDH2NPC1MAPT | |
| SCHEMBL7877675 | 0.72 | GABRA1 (0.37) | PRMT6IDH1IDH2NPC1MAPT | |
| SCHEMBL13719550 | 0.71 | IDH1 (0.44) | PRMT6IDH1IDH2NPC1MAPT | |
| SCHEMBL8131650 | 0.70 | PRMT6 (0.42) | PRMT6IDH1IDH2NPC1MAPT | |
| SCHEMBL13719485 | 0.70 | IDH1 (0.51) | PRMT6IDH1IDH2NPC1MAPT | |
| SCHEMBL5209985 | 0.69 | HSP90AA1 (0.39) | PRMT6IDH1IDH2MAPTRAB9A | |
| SCHEMBL5206965 | 0.69 | CNR2 (0.47) | NPC1MAPTRAB9A | |
| SCHEMBL7873623 | 0.69 | ALDH1A1 (0.44) | MAPTPOLB | |
| SCHEMBL6723685 | 0.69 | PRMT6 (0.37) | PRMT6IDH1IDH2NPC1MAPT | |
| SCHEMBL12531812 | 0.68 | IDH1 (0.43) | PRMT6IDH1IDH2NPC1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1421080-B1 | N-HETEROCYCLYL SUBSTITUTED THIENYLOXY-PYRIMIDINES USED AS HERBICIDES | BASF AG (DE) | 2005-02-09 | — | — | EP | disclosed |
| US-20040198758-A1 | N-heterocyclyl substituted thienyloxy-pyrimidines used as herbicides | BASF AKTIENGESELLSCHAFT (DE) | 2004-10-07 | — | — | US | disclosed |
| US-6172005-B1 | CONTROLLING UNDESIRABLE VEGETATION | E. I. DU PONT DE NEMOURS AND COMPANY | 2001-01-09 | — | — | US | disclosed |
| EP-0970072-A1 | HETEROARYL AZOLE HERBICIDES | E.I. DUPONT DE NEMOURS AND COMPANY (US) | 2000-01-12 | — | — | EP | disclosed |
| WO-1998040379-A1 | HETEROARYL AZOLE HERBICIDES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1998-09-17 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040198758-A1 | N-heterocyclyl substituted thienyloxy-pyrimidines used as herbicides | CBR3, CBR1, CBX8 | PRMT6 2296/4885IDH1 214/4885IDH2 361/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.