Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 2/20 | 0.33 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.33 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.33 |
| ▸ | GHSR | Q92847 | 1/20 | 0.32 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6184906 | 1.00 | BRD4 (0.33) | BRD4CREBBPPAX8GHSRMAPK10 | |
| SCHEMBL6184913 | 0.71 | NAMPT (0.41) | GHSRMAPK10EPHX2 | |
| SCHEMBL15218847 | 0.70 | GHSR (0.41) | BRD4CREBBPGHSREPHX2 | |
| SCHEMBL5836124 | 0.69 | GHSR (0.41) | BRD4CREBBPPAX8GHSR | |
| SCHEMBL23699419 | 0.66 | HTR2C (0.37) | BRD4PAX8GHSRL3MBTL1 | |
| SCHEMBL20904051 | 0.65 | OPRM1 (0.59) | — | |
| SCHEMBL20640233 | 0.65 | OPRM1 (0.44) | BRD4 | |
| SCHEMBL7607211 | 0.65 | ASGR1 (0.33) | — | |
| SCHEMBL5556488 | 0.64 | NPY5R (0.49) | MAPK1EPHX2 | |
| SCHEMBL21084775 | 0.64 | PAX8 (0.46) | BRD4CREBBPPAX8L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050256166-A1 | Nitrogen-containing compounds | ONO PHARMACEUTICAL CO., LTD. (JP) | 2005-11-17 | — | — | US | disclosed |
| EP-1535906-A1 | NITROGEN-CONTAINING COMPOUNDS | ONO PHARMACEUTICAL CO., LTD. (JP) | 2005-06-01 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050256166-A1 | Nitrogen-containing compounds | DPP4, DPP3, DPP8 | BRD4 199/4885CREBBP 3412/4885PAX8 334/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.