Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18733302 | 0.86 | HPGD (0.53) | TSHRSMN1; SMN2ALDH1A1HPGDHTT | |
| SCHEMBL23056646 | 0.85 | HPGD (0.57) | TSHRSMN1; SMN2ALDH1A1HPGDLMNA | |
| SCHEMBL18700834 | 0.85 | HPGD (0.57) | TSHRSMN1; SMN2ALDH1A1HPGDLMNA | |
| SCHEMBL2106193 | 0.83 | TDP1 (0.49) | MAPK1RECQLTSHRSMN1; SMN2MAPT | |
| SCHEMBL21822042 | 0.80 | RECQL (0.50) | MAPK1RECQLTSHRSMN1; SMN2MAPT | |
| SCHEMBL20405434 | 0.79 | ALDH1A1 (0.61) | MAPK1RECQLTSHRSMN1; SMN2ALDH1A1 | |
| SCHEMBL11184712 | 0.77 | ALDH1A1 (0.72) | MAPK1RECQLTSHRSMN1; SMN2ALDH1A1 | |
| SCHEMBL11158442 | 0.74 | TSHR (0.65) | MAPK1RECQLTSHRSMN1; SMN2ALDH1A1 | |
| SCHEMBL7893827 | 0.70 | THRB (0.43) | SMN1; SMN2MAPTALDH1A1TDP1HTT | |
| SCHEMBL18485319 | 0.70 | EPHX2 (0.51) | MAPK1RECQLTSHRSMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6979741-B2 | Acetyl-CoA carboxylase inhibitors | PFIZER INC. (US) | 2005-12-27 | — | — | US | disclosed |
| EP-1478437-B1 | ACC INHIBITORS | PFIZER PROD INC (US) | 2005-08-31 | — | — | EP | disclosed |
| US-20030187254-A1 | Acetyl-CoA carboxylase inhibitors | PFIZER INC. | 2003-10-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030187254-A1 | Acetyl-CoA carboxylase inhibitors | ACACA, ACACB, ACAT1 | MAPK1 2680/4885RECQL 2586/4885TSHR 4391/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.