SCHEMBL618563

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL10189225	0.93	SMN1; SMN2 (0.39)	ERN1KDM4EMAPTNPC1TDP1
	SCHEMBL617798	0.89	KDM4E (0.45)	ERN1KDM4EMAPTNPC1ALDH1A1
	SCHEMBL615526	0.87	TGFBR1 (0.39)	ERN1KDM4ENPC1ALDH1A1SMN1; SMN2
	SCHEMBL10189252	0.82	TGFBR1 (0.35)	ERN1KDM4ENPC1ALDH1A1SMN1; SMN2
	SCHEMBL1167971	0.80	ERN1 (0.43)	ERN1KDM4EMAPTNPC1TDP1
	SCHEMBL618238	0.78	TUBB4A (0.56)	TUBB4ATUBBTUBA3CTUBA1BTUBA4A
	SCHEMBL618017	0.78	TUBB4A (0.58)	TUBB4ATUBBTUBA3CTUBA1BTUBA4A
	SCHEMBL619216	0.78	TUBB4A (0.58)	TUBB4ATUBBTUBA3CTUBA1BTUBA4A
	SCHEMBL616144	0.78	TUBB4A (0.44)	KDM4EALDH1A1SMN1; SMN2MEN1KMT2A
	SCHEMBL616256	0.78	MEN1 (0.45)	NPC1ALDH1A1SMN1; SMN2RAB9AMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.