SCHEMBL615526

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL10189252	0.94	TGFBR1 (0.35)	TGFBR1ACVR1TUBB4ATUBBTUBA3C
	SCHEMBL618563	0.87	ERN1 (0.42)	TUBB4ATUBBTUBA3CTUBA1BTUBA4A
	SCHEMBL617873	0.87	ALDH1A1 (0.40)	ALDH1A1KDM4EMEN1HPGDKMT2A
	SCHEMBL10189225	0.81	SMN1; SMN2 (0.39)	ALDH1A1KDM4EMEN1KMT2ASMN1; SMN2
	SCHEMBL1168310	0.81	SCN9A (0.39)	TGFBR1ACVR1TUBB4ATUBBTUBA3C
	SCHEMBL617798	0.79	KDM4E (0.45)	ALDH1A1KDM4EMEN1KMT2ASMN1; SMN2
	SCHEMBL619368	0.78	PTGS2 (0.41)	TGFBR1ACVR1TUBB4ATUBBTUBA3C
	SCHEMBL616144	0.77	TUBB4A (0.44)	TUBB4ATUBBTUBA3CTUBA1BTUBA4A
	SCHEMBL10189277	0.77	PRKAB2 (0.32)	ALDH1A1MAPK1MEN1KMT2ASMN1; SMN2
	SCHEMBL1168712	0.76	MEN1 (0.44)	TGFBR1ACVR1TUBB4ATUBBTUBA3C

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.