SCHEMBL6186300

SCHEMBL6186300

N=c1sc2cc(F)ccc2n1CC1CCNCC1

nearest known ligand 0.39

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
SLC6A4 P31645 1/20 0.38
PLK1 P53350 3/20 0.36
CCR3 P51677 1/20 0.36
RIPK3 Q9Y572 1/20 0.35
CNR2 P34972 3/20 0.35
FEN1 P39748 1/20 0.34
MAPK9 P45984 1/20 0.33
KDM1A O60341 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6188419 0.85 DRD2 (0.39) SLC6A4CNR2FEN1KDM1A
SCHEMBL6189841 0.85 PARP10 (0.36) CNR2FEN1KDM1A
SCHEMBL6189826 0.85 PLK1 (0.41) SLC6A4PLK1CCR3RIPK3CNR2
SCHEMBL6190227 0.84 CNR2 (0.37) SLC6A4CNR2KDM1A
SCHEMBL6187144 0.81 ALDH1A1 (0.51)
SCHEMBL6187294 0.81 F12 (0.41) SLC6A4FEN1
SCHEMBL6188183 0.81 SCN4A (0.42) RIPK3CNR2KDM1A
SCHEMBL6191400 0.80 CNR2 (0.38) CNR2
Hydrochloric Acid SCHEMBL6187924 0.75 HTR2A (0.47)
Bromide SCHEMBL9780489 0.70 KCNQ3 (0.42) CNR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1043319-B1 NOVEL ALKYLAMINO DERIVATIVES MITSUBISHI CHEM CORP (JP) 2005-03-16 EP disclosed
EP-1043319-A1 NOVEL ALKYLAMINO DERIVATIVES MITSUBISHI CHEMICAL CORPORATION (JP) 2000-10-11 EP disclosed