Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP10 | Q53GL7 | 4/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | BRD4 | O60885 | 1/20 | 0.35 |
| ▸ | CNR2 | P34972 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | FEN1 | P39748 | 1/20 | 0.34 |
| ▸ | KDM1A | O60341 | 2/20 | 0.33 |
| ▸ | PARP15 | Q460N3 | 2/20 | 0.33 |
| ▸ | PARP14 | Q460N5 | 2/20 | 0.33 |
| ▸ | TNKS2 | Q9H2K2 | 2/20 | 0.33 |
| ▸ | PARP2 | Q9UGN5 | 2/20 | 0.33 |
| ▸ | HTR2C | P28335 | 2/20 | 0.33 |
| ▸ | TNKS | O95271 | 1/20 | 0.33 |
| ▸ | PARP1 | P09874 | 1/20 | 0.33 |
| ▸ | TIPARP | Q7Z3E1 | 1/20 | 0.33 |
| ▸ | PARP16 | Q8N5Y8 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6187775 | 0.85 | CNR2 (0.40) | PARP10NPC1RAB9AATMBRD4 | |
| SCHEMBL6188419 | 0.85 | DRD2 (0.39) | NPC1RAB9ACNR2FEN1KDM1A | |
| SCHEMBL6186300 | 0.85 | SLC6A4 (0.38) | CNR2FEN1KDM1A | |
| SCHEMBL6187144 | 0.84 | ALDH1A1 (0.51) | PARP10MEN1KMT2APARP15TNKS2 | |
| SCHEMBL6190227 | 0.81 | CNR2 (0.37) | CNR2KDM1AHTR2C | |
| SCHEMBL6187294 | 0.81 | F12 (0.41) | MEN1CYP2D6KMT2AFEN1 | |
| SCHEMBL6192369 | 0.80 | P2RX3 (0.43) | NPC1RAB9AATMFEN1 | |
| SCHEMBL6188183 | 0.79 | SCN4A (0.42) | CNR2KDM1AHTR2C | |
| Hydrochloric Acid SCHEMBL6190508 | 0.72 | HTR2A (0.44) | MEN1KMT2AHTR2COPRM1 | |
| SCHEMBL9771416 | 0.71 | MIF (0.48) | MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1043319-B1 | NOVEL ALKYLAMINO DERIVATIVES | MITSUBISHI CHEM CORP (JP) | 2005-03-16 | — | — | EP | disclosed |
| EP-1043319-A1 | NOVEL ALKYLAMINO DERIVATIVES | MITSUBISHI CHEMICAL CORPORATION (JP) | 2000-10-11 | — | — | EP | disclosed |