Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | NPY1R | P25929 | 1/20 | 0.46 |
| ▸ | NPY2R | P49146 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 6/20 | 0.44 |
| ▸ | SAE1 | Q9UBE0 | 2/20 | 0.44 |
| ▸ | UBA2 | Q9UBT2 | 2/20 | 0.44 |
| ▸ | BLM | P54132 | 1/20 | 0.44 |
| ▸ | UBE2I | P63279 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | CTSV | O60911 | 1/20 | 0.40 |
| ▸ | CTSL | P07711 | 1/20 | 0.40 |
| ▸ | PARP1 | P09874 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6186570 | 0.92 | ALDH1A1 (0.51) | ALDH1A1MEN1KMT2APOLBPKM | |
| SCHEMBL6187137 | 0.85 | ALDH1A1 (0.45) | ALDH1A1MEN1KMT2APOLBPKM | |
| SCHEMBL6184844 | 0.83 | ALDH1A1 (0.53) | ALDH1A1MEN1KMT2APOLBPKM | |
| SCHEMBL6188924 | 0.82 | LMNA (0.39) | ALDH1A1MEN1KMT2APOLBPKM | |
| SCHEMBL28524078 | 0.79 | MEN1 (0.58) | ALDH1A1MEN1KMT2APOLBPKM | |
| SCHEMBL6186801 | 0.79 | ALDH1A1 (0.51) | ALDH1A1MEN1KMT2APOLBPKM | |
| SCHEMBL6186247 | 0.77 | ALDH1A1 (0.67) | ALDH1A1MEN1KMT2APOLBPKM | |
| SCHEMBL5327852 | 0.76 | ALDH1A1 (0.68) | ALDH1A1MEN1KMT2APOLBPKM | |
| SCHEMBL28362604 | 0.76 | POLB (0.59) | ALDH1A1MEN1KMT2APOLBPKM | |
| SCHEMBL11250386 | 0.75 | ALDH1A1 (0.56) | ALDH1A1MEN1KMT2APOLBPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1554271-A1 | SUBSTITUTED INDOLES AND THEIR USE AS HCV INHIBITORS | Rigel Pharmaceuticals, Inc. (US) | 2005-07-20 | — | — | EP | disclosed |
| WO-2004035571-A1 | SUBSTITUTED INDOLES AND THEIR USE AS HCV INHIBITORS | RIGEL PHARMACEUTICALS, INC. (US) | 2004-04-29 | — | — | WO | disclosed |