Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 7/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.58 |
| ▸ | ESR1 | P03372 | 2/20 | 0.58 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.58 |
| ▸ | RECQL | P46063 | 1/20 | 0.58 |
| ▸ | ELANE | P08246 | 2/20 | 0.53 |
| ▸ | RAB9A | P51151 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | ACHE | P22303 | 2/20 | 0.45 |
| ▸ | THRB | P10828 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.42 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.42 |
| ▸ | RELA | Q04206 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10192354 | 0.86 | SMN1; SMN2 (0.55) | KMT2ASMN1; SMN2ESR1HIF1ARECQL | |
| SCHEMBL5042252 | 0.84 | KMT2A (0.53) | KMT2ASMN1; SMN2ESR1HIF1ARECQL | |
| SCHEMBL312147 | 0.84 | KMT2A (0.76) | KMT2ASMN1; SMN2ESR1HIF1ARECQL | |
| SCHEMBL1512672 | 0.82 | KMT2A (0.63) | KMT2ASMN1; SMN2ESR1HIF1ARECQL | |
| SCHEMBL11445596 | 0.82 | KMT2A (0.73) | KMT2ASMN1; SMN2ESR1HIF1ARECQL | |
| SCHEMBL27902979 | 0.81 | KMT2A (0.61) | KMT2ASMN1; SMN2ESR1HIF1ARECQL | |
| SCHEMBL170186 | 0.81 | KMT2A (0.61) | KMT2ASMN1; SMN2ESR1HIF1ARECQL | |
| SCHEMBL6794454 | 0.81 | LMNA (0.55) | KMT2ASMN1; SMN2ESR1ELANERAB9A | |
| SCHEMBL20342007 | 0.80 | KMT2A (0.56) | KMT2ASMN1; SMN2ESR1HIF1ARECQL | |
| SCHEMBL27864662 | 0.80 | ACHE (0.56) | KMT2ASMN1; SMN2ESR1HIF1ARECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107365297-A | A kind of Preparation Method And Their Intermediate of the benzyl propionate derivant of 2 methyl 2 ' | 罗欣生物科技（上海）有限公司 | 2017-11-21 | — | — | CN | disclosed |
| CN-103936716-B | Tool muscarinic receptor antagonists and the diamide compound of beta 2 adrenoreceptor agonists activity | 施万呼吸有限责任公司 | 2016-09-07 | — | — | CN | disclosed |
| CN-103936716-A | Diamide compounds having muscarinic receptor antagonist and beta 2 adrenoceptor agonist activity | THERAVANCE INC | 2014-07-23 | — | — | CN | disclosed |
| CN-102405218-B | Muscarinic receptor antagonists and beta2Diamide compounds having adrenergic receptor agonist activity | THERAVANCE INC | 2014-06-04 | — | — | CN | disclosed |
| CN-102405218-A | Muscarinic receptor antagonists and beta2Diamide compounds having adrenergic receptor agonist activity | THERAVANCE INC | 2012-04-04 | — | — | CN | disclosed |