Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.32 |
| ▸ | MMP1 | P03956 | 1/20 | 0.30 |
| ▸ | MMP2 | P08253 | 1/20 | 0.30 |
| ▸ | MMP9 | P14780 | 1/20 | 0.30 |
| ▸ | TEAD4 | Q15561 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6191091 | 0.85 | KDM4E (0.34) | CYP1A2L3MBTL1NR3C2 | |
| SCHEMBL6189357 | 0.81 | CNR2 (0.33) | CNR2CYP1A2 | |
| SCHEMBL6189555 | 0.80 | CNR2 (0.36) | CNR2CYP1A2L3MBTL1MMP1MMP2 | |
| SCHEMBL6192154 | 0.79 | CYP1A2 (0.34) | CNR2CYP1A2MMP2MMP9 | |
| SCHEMBL6191973 | 0.79 | CYP2C9 (0.36) | L3MBTL1NR3C2 | |
| SCHEMBL6174563 | 0.78 | LDHA (0.35) | CNR2CYP1A2NR3C2TEAD4 | |
| SCHEMBL6174566 | 0.78 | LDHA (0.35) | CNR2CYP1A2NR3C2TEAD4 | |
| SCHEMBL6191050 | 0.75 | CYP1A2 (0.34) | CNR2CYP1A2L3MBTL1NR3C2MMP1 | |
| SCHEMBL6189248 | 0.74 | CYP1A2 (0.34) | CNR2CYP1A2 | |
| SCHEMBL6178714 | 0.72 | MLNR (0.40) | CNR2CYP1A2NR3C2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1203770-B1 | Pyran-2-ones and 5,6-dihydropyran-2-ones useful for treating hyperplasia and other diseases | UPJOHN CO (US) | 2005-03-09 | — | — | EP | claimed |
| EP-0668860-B1 | PYRAN-2-ONES AND 5,6-DIHYDROPYRAN-2-ONES USEFUL FOR TREATING HIV AND OTHER RETROVIRUSES | UPJOHN CO (US) | 2002-09-11 | — | — | EP | claimed |