Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 5/20 | 0.42 |
| ▸ | MTNR1B | P49286 | 4/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | PLA2G2A | P14555 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5093055 | 0.87 | MEN1 (0.40) | MTNR1AMTNR1BMAPTHTTKDM4E | |
| SCHEMBL6193839 | 0.83 | MTNR1A (0.46) | MTNR1AMTNR1BMAPTHTTKDM4E | |
| SCHEMBL6195167 | 0.78 | MTNR1A (0.51) | MTNR1AMTNR1BMAPTKDM4EALDH1A1 | |
| SCHEMBL28394719 | 0.75 | GRIK2 (0.50) | MAPTHTTKDM4EALDH1A1L3MBTL1 | |
| SCHEMBL6193835 | 0.72 | MTNR1A (0.66) | MTNR1AMTNR1BMAPTKDM4EALDH1A1 | |
| SCHEMBL5094722 | 0.71 | TACR1 (0.39) | MAPTHTTKDM4EALDH1A1L3MBTL1 | |
| SCHEMBL6193060 | 0.71 | MAT2A (0.37) | ALDH1A1KMT2APOLBNPSR1 | |
| Oxalic Acid SCHEMBL5094988 | 0.71 | PTGDR2 (0.38) | MAPTALDH1A1 | |
| SCHEMBL5094694 | 0.71 | PER2 (0.35) | MAPTKDM4EALDH1A1L3MBTL1KMT2A | |
| SCHEMBL5089912 | 0.71 | NTRK1 (0.38) | MAPTKDM4EL3MBTL1KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1517909-A2 | NOVEL TETRACYCLIC ARYLCARBONYL INDOLES HAVING SEROTONIN RECEPTOR AFFINITY USEFUL AS THERAPEUTIC AGENTS, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | Suven Life Sciences Limited (IN) | 2005-03-30 | — | — | EP | disclosed |
| WO-2004000205-A2 | NOVEL TETRACYCLIC ARYLCARBONYL INDOLES HAVING SEROTONIN RECEPTOR AFFINITY USEFUL AS THERAPEUTIC AGENTS, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | SUVEN LIFE SCIENCES LIMITED (IN) | 2003-12-31 | — | — | WO | disclosed |