Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 10/20 | 0.45 |
| ▸ | SLC6A2 | P23975 | 5/20 | 0.45 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.37 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.37 |
| ▸ | MITF | O75030 | 1/20 | 0.37 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.36 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.36 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.36 |
| ▸ | KDM1A | O60341 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL147285 | 0.83 | SLC6A4 (0.44) | SLC6A4SLC6A2SLC6A3MEN1KMT2A | |
| SCHEMBL1841972 | 0.83 | SLC6A4 (0.48) | SLC6A4SLC6A2SLC6A3MEN1KMT2A | |
| SCHEMBL1841974 | 0.83 | SLC6A4 (0.48) | SLC6A4SLC6A2SLC6A3MEN1KMT2A | |
| Faxeladol SCHEMBL5686250 | 0.81 | SLC6A4 (0.50) | SLC6A4SLC6A2MEN1KMT2AOPRM1 | |
| Faxeladol SCHEMBL28793358 | 0.81 | SLC6A4 (0.50) | SLC6A4SLC6A2MEN1KMT2AOPRM1 | |
| Faxeladol SCHEMBL354208 | 0.81 | SLC6A4 (0.50) | SLC6A4SLC6A2MEN1KMT2AOPRM1 | |
| Faxeladol SCHEMBL149508 | 0.81 | SLC6A4 (0.50) | SLC6A4SLC6A2MEN1KMT2AOPRM1 | |
| Faxeladol SCHEMBL149507 | 0.81 | SLC6A4 (0.50) | SLC6A4SLC6A2MEN1KMT2AOPRM1 | |
| Faxeladol SCHEMBL616828 | 0.81 | SLC6A4 (0.50) | SLC6A4SLC6A2MEN1KMT2AOPRM1 | |
| Faxeladol SCHEMBL30616185 | 0.81 | SLC6A4 (0.50) | SLC6A4SLC6A2MEN1KMT2AOPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101262857-A | 3-(2-dimethylaminomethyl cyclohexyl) phenol retard formulation | GRUENENTHAL GMBH (DE) | 2008-09-10 | — | — | CN | claimed |
| US-20120039963-A1 | 3-(2-Dimethlaminomethyl Cyclohexyl)Phenol Retard Formulation | GRUENENTHAL GMBH (DE) | 2012-02-16 | — | — | US | disclosed |
| CN-1697651-B | 1-phenyl-2-dimethylaminomethyl cyclohexane compounds and therapies for depressive symptoms, pain and incontinence | KRAUSE GEORG | 2011-09-21 | — | — | CN | disclosed |
| CN-101412681-A | Method for preparing 3-(2-dimethyl aminomethyl-cyclohexyl)-phenol acetic ester hydrochloride | UNIV TONGJI (CN) | 2009-04-22 | — | — | CN | disclosed |
| CN-1697651-A | 1-phenyl-2-dimethylaminomethyl cyclohexane compounds and therapies for depressive symptoms, pain and incontinence | KRAUSE GEORG (DE) | 2005-11-16 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120039963-A1 | 3-(2-Dimethlaminomethyl Cyclohexyl)Phenol Retard Formulation | MC2R, MC3R, HTR3C | SLC6A4 1653/4885SLC6A2 582/4885SLC6A3 481/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.