Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | P2RX3 | P56373 | 3/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | MCHR1 | Q99705 | 3/20 | 0.31 |
| ▸ | PDE1C | Q14123 | 1/20 | 0.30 |
| ▸ | HTR2C | P28335 | 1/20 | 0.30 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6195209 | 0.88 | HTT (0.35) | HTTSMN1; SMN2MEN1ALDH1A1KMT2A | |
| SCHEMBL6198184 | 0.88 | HTT (0.38) | HTTSMN1; SMN2MEN1ALDH1A1KMT2A | |
| SCHEMBL6197503 | 0.86 | ALDH1A1 (0.34) | HTTSMN1; SMN2MEN1ALDH1A1KMT2A | |
| SCHEMBL8850256 | 0.83 | HTT (0.34) | HTTSMN1; SMN2MEN1ALDH1A1KMT2A | |
| SCHEMBL6197787 | 0.82 | LMNA (0.42) | LMNAGAAPOLB | |
| SCHEMBL6198797 | 0.81 | MAOB (0.37) | HTTSMN1; SMN2MEN1ALDH1A1KMT2A | |
| SCHEMBL6200100 | 0.77 | HTT (0.38) | HTTSMN1; SMN2MEN1ALDH1A1KMT2A | |
| SCHEMBL6198833 | 0.77 | HTT (0.38) | HTTSMN1; SMN2MEN1ALDH1A1KMT2A | |
| SCHEMBL6196257 | 0.76 | HTT (0.38) | HTTSMN1; SMN2MEN1ALDH1A1KMT2A | |
| SCHEMBL6196690 | 0.76 | HTT (0.37) | HTTSMN1; SMN2MEN1ALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0768302-B1 | Hydroxypyridinones | NOVARTIS AG (CH) | 2005-07-06 | — | — | EP | disclosed |
| US-5688815-A | COMPOUNDS FOR REMOVAL OF EXCESS IRON IN MAMMALS | CIBA GEIGY CORPORATION (US) | 1997-11-18 | — | — | US | disclosed |
| EP-0768302-A2 | Hydroxypyridinones | Novartis AG (CH) | 1997-04-16 | — | — | EP | disclosed |