Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8850308 | 0.89 | HTT (0.34) | HTTSMN1; SMN2MEN1ALDH1A1HPGD | |
| SCHEMBL6198184 | 0.87 | HTT (0.38) | HTTSMN1; SMN2MEN1ALDH1A1HPGD | |
| SCHEMBL6196641 | 0.83 | HTT (0.35) | HTTSMN1; SMN2MEN1ALDH1A1HPGD | |
| SCHEMBL6198797 | 0.83 | MAOB (0.37) | HTTSMN1; SMN2MEN1ALDH1A1HPGD | |
| SCHEMBL8850715 | 0.83 | LMNA (0.40) | LMNAGAA | |
| SCHEMBL6197503 | 0.81 | ALDH1A1 (0.34) | HTTSMN1; SMN2MEN1ALDH1A1HPGD | |
| SCHEMBL6198799 | 0.75 | HTT (0.33) | HTTSMN1; SMN2MEN1ALDH1A1HPGD | |
| SCHEMBL6198833 | 0.75 | HTT (0.38) | HTTSMN1; SMN2MEN1ALDH1A1HPGD | |
| SCHEMBL6200100 | 0.75 | HTT (0.38) | HTTSMN1; SMN2MEN1ALDH1A1HPGD | |
| SCHEMBL6196257 | 0.75 | HTT (0.38) | HTTSMN1; SMN2MEN1ALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5688815-A | COMPOUNDS FOR REMOVAL OF EXCESS IRON IN MAMMALS | CIBA GEIGY CORPORATION (US) | 1997-11-18 | — | — | US | disclosed |