Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 1/20 | 0.55 |
| ▸ | EGFR | P00533 | 2/20 | 0.53 |
| ▸ | ERBB2 | P04626 | 2/20 | 0.53 |
| ▸ | GSK3B | P49841 | 2/20 | 0.52 |
| ▸ | RAB9A | P51151 | 4/20 | 0.50 |
| ▸ | NPC1 | O15118 | 3/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.48 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.48 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.48 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.48 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.48 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.48 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.48 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.48 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.48 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.48 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6203410 | 1.00 | PTPN1 (0.55) | PTPN1EGFRERBB2GSK3BRAB9A | |
| SCHEMBL8584136 | 0.90 | GSK3B (0.61) | GSK3BRAB9ANPC1MAPTHDAC3 | |
| SCHEMBL29985867 | 0.90 | GSK3B (0.61) | GSK3BRAB9ANPC1MAPTHDAC3 | |
| SCHEMBL6201900 | 0.90 | RAB9A (0.59) | PTPN1RAB9ANPC1MAPTLMNA | |
| SCHEMBL7854876 | 0.83 | NPC1 (0.68) | PTPN1GSK3BRAB9ANPC1MAPT | |
| SCHEMBL5724883 | 0.83 | RAB9A (0.68) | PTPN1RAB9ANPC1MAPTALDH1A1 | |
| SCHEMBL8044783 | 0.83 | NPC1 (0.68) | PTPN1GSK3BRAB9ANPC1MAPT | |
| SCHEMBL7167952 | 0.83 | SRD5A2 (0.62) | PTPN1RAB9ANPC1MAPTALDH1A1 | |
| SCHEMBL20262696 | 0.82 | NPC1 (0.56) | PTPN1GSK3BRAB9ANPC1HDAC1 | |
| Ethylene SCHEMBL10765273 | 0.82 | LMNA (0.41) | PTPN1EGFRERBB2MAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180006236-A1 | ORGANIC COMPOUNDS AND ELECTRONIC DEVICE COMPRISING ORGANIC LAYER COMPRISING ORGANIC COMPOUNDS | DOW GLOBAL TECHNOLOGIES LLC (US) | 2018-01-04 | — | — | US | disclosed |
| US-20180006236-A1 | ORGANIC COMPOUNDS AND ELECTRONIC DEVICE COMPRISING ORGANIC LAYER COMPRISING ORGANIC COMPOUNDS | DOW GLOBAL TECHNOLOGIES LLC (US) | 2018-01-04 | — | — | US | disclosed |
| WO-2016101865-A1 | ORGANIC COMPOUNDS AND ELECTRONIC DEVICE COMPRISING ORGANIC LAYER COMPRISING ORGANIC COMPOUNDS | DOW GLOBAL TECHNOLOGIES LLC (US) | 2016-06-30 | — | — | WO | disclosed |
| US-20050272036-A1 | Ketones | ASTRAZENECA AB (SE) | 2005-12-08 | — | — | US | disclosed |
| CN-1681763-A | Chemical compounds | ASTRAZENECA AB (SE) | 2005-10-12 | — | — | CN | disclosed |
| EP-1549600-A1 | KETONES | AstraZeneca AB (SE) | 2005-07-06 | — | — | EP | disclosed |
| WO-2004011410-A1 | CHEMICAL COMPOUNDS | ASTRAZENECA AB (SE) | 2004-02-05 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180006236-A1 | ORGANIC COMPOUNDS AND ELECTRONIC DEVICE COMPRISING ORGANIC LAYER COMPRISING ORGANIC COMPOUNDS | OR10J3, OCIAD2, VDAC2 | PTPN1 3990/4885EGFR 2628/4885ERBB2 4118/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.