Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 3/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | USP2 | O75604 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | SUCNR1 | Q9BXA5 | 2/20 | 0.47 |
| ▸ | MGAM | O43451 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | SI | P14410 | 1/20 | 0.46 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.46 |
| ▸ | TBXAS1 | P24557 | 2/20 | 0.46 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.46 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.46 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | CYP3A5 | P20815 | 1/20 | 0.45 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10919976 | 0.81 | CYP19A1 (0.50) | CYP19A1LMNAALDH1A1SUCNR1TBXAS1 | |
| SCHEMBL2680346 | 0.80 | KMT2A (0.48) | CYP19A1LMNAKMT2AMEN1USP2 | |
| SCHEMBL6678494 | 0.80 | KMT2A (0.48) | CYP19A1LMNAKMT2AMEN1USP2 | |
| SCHEMBL6678491 | 0.79 | MEN1 (0.47) | CYP19A1LMNAKMT2AMEN1USP2 | |
| SCHEMBL6201493 | 0.78 | LMNA (0.46) | CYP19A1LMNAKMT2AMEN1USP2 | |
| SCHEMBL6204707 | 0.77 | MGAM (0.49) | LMNAKMT2AMEN1USP2ALDH1A1 | |
| SCHEMBL11737642 | 0.76 | CYP19A1 (0.62) | CYP19A1LMNAALDH1A1TBXAS1PDE4D | |
| SCHEMBL11990053 | 0.76 | TBXAS1 (0.63) | LMNATBXAS1PDE4DHPGDHTT | |
| SCHEMBL28036009 | 0.75 | L3MBTL1 (0.63) | LMNAKMT2AMEN1ALDH1A1PDPK1 | |
| Ammonia Solution, Strong SCHEMBL6000489 | 0.75 | CYP19A1 (0.60) | CYP19A1LMNAALDH1A1TBXAS1PDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1549600-A1 | KETONES | AstraZeneca AB (SE) | 2005-07-06 | — | — | EP | claimed |
| WO-2004011410-A1 | CHEMICAL COMPOUNDS | ASTRAZENECA AB (SE) | 2004-02-05 | — | — | WO | claimed |
| EP-1549600-A1 | KETONES | AstraZeneca AB (SE) | 2005-07-06 | — | — | EP | disclosed |
| WO-2004011410-A1 | CHEMICAL COMPOUNDS | ASTRAZENECA AB (SE) | 2004-02-05 | — | — | WO | disclosed |