Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | PLOD2 | O00469 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | MGAM | O43451 | 1/20 | 0.42 |
| ▸ | SI | P14410 | 1/20 | 0.42 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.42 |
| ▸ | FNTA | P49354 | 1/20 | 0.41 |
| ▸ | FNTB | P49356 | 1/20 | 0.41 |
| ▸ | SUCNR1 | Q9BXA5 | 2/20 | 0.41 |
| ▸ | APP | P05067 | 1/20 | 0.41 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.41 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6202065 | 0.84 | POLB (0.42) | KMT2AGAAMGAMSIMGAM2 | |
| SCHEMBL6201652 | 0.80 | ALDH1A1 (0.43) | LMNAALDH1A1MEN1KMT2ATSHR | |
| SCHEMBL6201073 | 0.78 | CYP19A1 (0.53) | LMNAALDH1A1MEN1USP2KMT2A | |
| SCHEMBL6204077 | 0.76 | MGAM (0.50) | LMNAMEN1KMT2ATSHRMAPT | |
| SCHEMBL6202787 | 0.75 | MGAM (0.52) | LMNAALDH1A1MEN1USP2KMT2A | |
| SCHEMBL7363506 | 0.73 | TBXAS1 (0.49) | LMNASMN1; SMN2 | |
| SCHEMBL6201491 | 0.73 | TSHR (0.50) | LMNAALDH1A1MEN1USP2KMT2A | |
| SCHEMBL6204707 | 0.72 | MGAM (0.49) | LMNAALDH1A1MEN1USP2KMT2A | |
| SCHEMBL7355559 | 0.71 | TBXAS1 (0.44) | LMNAALDH1A1SMN1; SMN2CYP2C19 | |
| SCHEMBL14073817 | 0.71 | PLOD2 (0.59) | LMNAALDH1A1MEN1KMT2APLOD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1549600-A1 | KETONES | AstraZeneca AB (SE) | 2005-07-06 | — | — | EP | claimed |
| WO-2004011410-A1 | CHEMICAL COMPOUNDS | ASTRAZENECA AB (SE) | 2004-02-05 | — | — | WO | claimed |
| EP-1549600-A1 | KETONES | AstraZeneca AB (SE) | 2005-07-06 | — | — | EP | disclosed |
| WO-2004011410-A1 | CHEMICAL COMPOUNDS | ASTRAZENECA AB (SE) | 2004-02-05 | — | — | WO | disclosed |