Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 3/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.47 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.47 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.47 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.47 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.47 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.47 |
| ▸ | CHRM1 | P11229 | 4/20 | 0.47 |
| ▸ | CHRM3 | P20309 | 4/20 | 0.47 |
| ▸ | CHRM2 | P08172 | 3/20 | 0.47 |
| ▸ | CHRM4 | P08173 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9327799 | 0.85 | KMT2A (0.50) | CYP1A2LMNACYP2D6CHRM1CHRM3 | |
| SCHEMBL2310025 | 0.84 | LMNA (0.62) | CYP1A2LMNACYP2D6CYP3A4CHRM1 | |
| SCHEMBL1560439 | 0.81 | AKT2 (0.41) | LMNACYP2D6L3MBTL1 | |
| SCHEMBL6055220 | 0.78 | MEN1 (0.43) | CYP1A2CYP2D6ALDH1A1SMN1; SMN2L3MBTL1 | |
| SCHEMBL4534323 | 0.78 | CYP1A2 (0.53) | CYP1A2LMNACYP2D6CYP3A4GABRA1 | |
| SCHEMBL9326757 | 0.78 | MEN1 (0.43) | CYP1A2CYP2D6ALDH1A1SMN1; SMN2L3MBTL1 | |
| SCHEMBL5084136 | 0.78 | LMNA (0.55) | CYP1A2LMNACYP2D6CYP3A4CHRM1 | |
| SCHEMBL30350798 | 0.76 | NOS2 (0.41) | CYP1A2LMNACYP3A4GABRA1GABRB2 | |
| SCHEMBL27965729 | 0.76 | LMNA (0.54) | CYP1A2LMNACYP2D6CYP3A4CHRM1 | |
| SCHEMBL29299737 | 0.75 | LMNA (0.53) | CYP1A2LMNACYP2D6CYP3A4CHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1562937-A2 | N-SUBSTITUTED PIPERIDINE DERIVATIVES AS SEROTONIN RECEPTOR AGENTS | Acadia Pharmaceuticals Inc. (US) | 2005-08-17 | — | — | EP | disclosed |
| WO-2004000808-A2 | N-SUBSTITUTED PIPERIDINE DERIVATIVES AS SEROTONIN RECEPTOR AGENTS | ACADIA PHARMACEUTICALS INC. (US) | 2003-12-31 | — | — | WO | disclosed |