Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | AKT2 | P31751 | 2/20 | 0.42 |
| ▸ | ROCK1 | Q13464 | 3/20 | 0.41 |
| ▸ | MYLK4 | Q86YV6 | 3/20 | 0.41 |
| ▸ | CTSD | P07339 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | ROCK2 | O75116 | 3/20 | 0.39 |
| ▸ | AKT1 | P31749 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | HRH2 | P25021 | 1/20 | 0.38 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.38 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.38 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.38 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6055220 | 1.00 | MEN1 (0.43) | MEN1KMT2AAKT2ROCK1MYLK4 | |
| SCHEMBL1560439 | 0.86 | AKT2 (0.41) | AKT2ROCK1MYLK4CTSDROCK2 | |
| SCHEMBL9327799 | 0.81 | KMT2A (0.50) | KMT2AROCK1MYLK4ALDH1A1ROCK2 | |
| SCHEMBL2169318 | 0.80 | ALDH1A1 (0.43) | MEN1KMT2AROCK1MYLK4ALDH1A1 | |
| SCHEMBL741751 | 0.80 | MEN1 (0.58) | MEN1KMT2ACTSDTDP1L3MBTL1 | |
| SCHEMBL2170749 | 0.79 | NOS2 (0.33) | ROCK1MYLK4ALDH1A1 | |
| SCHEMBL6201346 | 0.78 | CYP1A2 (0.48) | ALDH1A1L3MBTL1CYP1A2CYP2D6SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL8550499 | 0.78 | MEN1 (0.56) | MEN1KMT2ACTSDTDP1L3MBTL1 | |
| Acetic Acid SCHEMBL9853044 | 0.74 | MEN1 (0.53) | MEN1KMT2ACTSDALDH1A1TDP1 | |
| SCHEMBL2205442 | 0.73 | SLC6A2 (0.54) | MEN1KMT2ACTSDALDH1A1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0424021-B1 | Antimuscarinic bronchodilators | PFIZER LTD (GB) | 1994-03-02 | — | — | EP | disclosed |
| US-5171744-A | Antimuscarinic bronchodilators | PFIZER INC. (US) | 1992-12-15 | — | — | US | disclosed |
| EP-0424021-A1 | Antimuscarinic bronchodilators | Pfizer Limited (GB) | 1991-04-24 | — | — | EP | disclosed |