Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.53 |
| ▸ | CTRB1 | P17538 | 2/20 | 0.51 |
| ▸ | ATM | Q13315 | 2/20 | 0.51 |
| ▸ | CASP1 | P29466 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | CTSK | P43235 | 3/20 | 0.49 |
| ▸ | KYNU | Q16719 | 1/20 | 0.49 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | CTSL | P07711 | 2/20 | 0.48 |
| ▸ | CTSS | P25774 | 2/20 | 0.48 |
| ▸ | ELANE | P08246 | 1/20 | 0.48 |
| ▸ | CTSB | P07858 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6538867 | 0.99 | TRPM8 (0.52) | TRPM8CTRB1ATMCASP1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL7212603 | 0.99 | TRPM8 (0.52) | TRPM8CTRB1ATMCASP1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL6939391 | 0.99 | TRPM8 (0.52) | TRPM8CTRB1ATMCASP1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL6933216 | 0.90 | CTRB1 (0.52) | TRPM8CTRB1ATMCASP1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL6941305 | 0.88 | CASP1 (0.48) | TRPM8CTRB1ATMCASP1CTSK | |
| Hydrochloric Acid SCHEMBL6940413 | 0.88 | CASP1 (0.48) | TRPM8CTRB1ATMCASP1CTSK | |
| Hydrochloric Acid SCHEMBL7421595 | 0.88 | CASP1 (0.48) | TRPM8CTRB1ATMCASP1CTSK | |
| SCHEMBL6200622 | 0.87 | CASP1 (0.56) | TRPM8CTRB1ATMCASP1CA12 | |
| SCHEMBL6941323 | 0.87 | CASP1 (0.56) | TRPM8CTRB1ATMCASP1CA12 | |
| SCHEMBL6937929 | 0.87 | CASP1 (0.56) | TRPM8CTRB1ATMCASP1CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1165532-B1 | ANTIBACTERIAL AGENTS | VERNALIS OXFORD LTD (GB) | 2005-01-12 | — | — | EP | disclosed |
| US-6503897-B1 | N-Formylhydroxylamine derivatives; veterinary medicine; grampositive and gramnegative bacteria | BRITISH BIOTECH PHARMACEUTICALS LTD. (GB) | 2003-01-07 | — | — | US | disclosed |
| EP-1165532-A1 | ANTIBACTERIAL AGENTS | BRITISH BIOTECH PHARMACEUTICALS LIMITED (GB) | 2002-01-02 | — | — | EP | disclosed |
| WO-2000058294-A1 | ANTIBACTERIAL AGENTS | BRITISH BIOTECH PHARMACEUTICALS LIMITED (GB) | 2000-10-05 | — | — | WO | disclosed |