Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP1 | P29466 | 12/20 | 0.56 |
| ▸ | CTRB1 | P17538 | 2/20 | 0.55 |
| ▸ | CA12 | O43570 | 1/20 | 0.51 |
| ▸ | CA1 | P00915 | 1/20 | 0.51 |
| ▸ | CA2 | P00918 | 1/20 | 0.51 |
| ▸ | CA9 | Q16790 | 1/20 | 0.51 |
| ▸ | ATM | Q13315 | 1/20 | 0.51 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6937929 | 1.00 | CASP1 (0.56) | CASP1CTRB1CA12CA1CA2 | |
| SCHEMBL6941323 | 1.00 | CASP1 (0.56) | CASP1CTRB1CA12CA1CA2 | |
| Hydrochloric Acid SCHEMBL6933216 | 0.88 | CTRB1 (0.52) | CASP1CTRB1CA12CA1CA2 | |
| SCHEMBL6201683 | 0.87 | TRPM8 (0.53) | CASP1CTRB1CA12CA1CA2 | |
| SCHEMBL6806205 | 0.86 | HTT (0.56) | CASP1CTRB1CA12CA1CA2 | |
| SCHEMBL14625712 | 0.86 | CTRB1 (0.64) | CTRB1CA12CA1CA2CA9 | |
| SCHEMBL10953605 | 0.86 | CTRB1 (0.64) | CTRB1CA12CA1CA2CA9 | |
| Hydrochloric Acid SCHEMBL6538867 | 0.85 | TRPM8 (0.52) | CASP1CTRB1CA12CA1CA2 | |
| Hydrochloric Acid SCHEMBL6939391 | 0.85 | TRPM8 (0.52) | CASP1CTRB1CA12CA1CA2 | |
| Hydrochloric Acid SCHEMBL7212603 | 0.85 | TRPM8 (0.52) | CASP1CTRB1CA12CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1165532-B1 | ANTIBACTERIAL AGENTS | VERNALIS OXFORD LTD (GB) | 2005-01-12 | — | — | EP | disclosed |
| US-6723727-B1 | VITRONECTIN RECEPTOR ANTAGONISTS; INHIBITORS OF BONE RESORPTION; OSTEOPOROSIS | HOECHST AKTIENGESELLSCHAFT (DE) | 2004-04-20 | — | — | US | disclosed |
| US-6503897-B1 | N-Formylhydroxylamine derivatives; veterinary medicine; grampositive and gramnegative bacteria | BRITISH BIOTECH PHARMACEUTICALS LTD. (GB) | 2003-01-07 | — | — | US | disclosed |
| EP-1165532-A1 | ANTIBACTERIAL AGENTS | BRITISH BIOTECH PHARMACEUTICALS LIMITED (GB) | 2002-01-02 | — | — | EP | disclosed |
| WO-2000058294-A1 | ANTIBACTERIAL AGENTS | BRITISH BIOTECH PHARMACEUTICALS LIMITED (GB) | 2000-10-05 | — | — | WO | disclosed |