Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AURKA | O14965 | 4/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | MERTK | Q12866 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 2/20 | 0.35 |
| ▸ | RPS6KB1 | P23443 | 4/20 | 0.35 |
| ▸ | TNK2 | Q07912 | 2/20 | 0.35 |
| ▸ | LCK | P06239 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6203462 | 0.83 | AURKA (0.42) | AURKAALDH1A1HPGDTSHRHSD17B10 | |
| SCHEMBL6200961 | 0.82 | AURKA (0.71) | AURKAALDH1A1HPGDTSHRHSD17B10 | |
| SCHEMBL6846664 | 0.82 | AURKA (0.55) | AURKAALDH1A1HPGDTSHRHSD17B10 | |
| SCHEMBL6202459 | 0.78 | ALDH1A1 (0.53) | AURKAALDH1A1HPGDTSHRHSD17B10 | |
| SCHEMBL6202985 | 0.75 | AURKA (0.87) | AURKAALDH1A1HPGDTSHRHSD17B10 | |
| SCHEMBL6203305 | 0.72 | AURKA (0.49) | AURKAALDH1A1HPGDTSHRHSD17B10 | |
| Hydrochloric Acid SCHEMBL6202056 | 0.72 | AURKA (0.51) | AURKAALDH1A1HPGDTSHRHSD17B10 | |
| SCHEMBL6203559 | 0.71 | ALDH1A1 (0.66) | AURKAALDH1A1HPGDTSHRHSD17B10 | |
| SCHEMBL6203768 | 0.71 | ALDH1A1 (0.66) | AURKAALDH1A1HPGDTSHRHSD17B10 | |
| Hydrochloric Acid SCHEMBL6841771 | 0.70 | AURKA (0.48) | AURKAALDH1A1HPGDTSHRHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1425283-B1 | NOVEL 4-AMINOFUROPYRIMIDINES AND THE USE THEREOF | BAYER HEALTHCARE AG (DE) | 2005-03-16 | — | — | EP | disclosed |