Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 5/20 | 0.47 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.44 |
| ▸ | EGFR | P00533 | 1/20 | 0.44 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.44 |
| ▸ | MAOB | P27338 | 5/20 | 0.42 |
| ▸ | MAOA | P21397 | 1/20 | 0.42 |
| ▸ | LCK | P06239 | 1/20 | 0.40 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.40 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.40 |
| ▸ | NSD2 | O96028 | 1/20 | 0.39 |
| ▸ | ABL1 | P00519 | 1/20 | 0.39 |
| ▸ | PPARG | P37231 | 1/20 | 0.39 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.39 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2093026 | 0.86 | ALOX5 (0.53) | BCHEALOX5MAOBMAOALCK | |
| SCHEMBL3846804 | 0.85 | MAPT (0.42) | MAOALMNA | |
| SCHEMBL27544006 | 0.82 | ALDH1A1 (0.39) | BCHEMAOBL3MBTL1 | |
| SCHEMBL28747010 | 0.82 | MAOB (0.44) | BCHEALOX5MAOBMAOACYP4F2 | |
| SCHEMBL2772599 | 0.81 | MAOB (0.49) | BCHEALOX5MAOBMAOACYP4F2 | |
| SCHEMBL3948493 | 0.79 | MAOB (0.58) | BCHEALOX5MAOBMAOACYP4F2 | |
| SCHEMBL6201987 | 0.78 | MAOB (0.50) | BCHEALOX5MAOBMAOACYP4F2 | |
| SCHEMBL7290118 | 0.76 | BCHE (0.60) | BCHEALOX5EGFRERBB2MAOB | |
| SCHEMBL2202368 | 0.76 | MAOB (0.58) | BCHEMAOB | |
| SCHEMBL28010652 | 0.75 | ALOX5 (0.45) | BCHEALOX5MAOBMAOACYP4F2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1503798-A | Antidepressant azaheterocyclylmethyl derivatives of oxacyclo-fused- [1,4] benzodioxans | — | 2004-06-09 | — | — | CN | disclosed |