Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNE2 | O96020 | 6/20 | 0.48 |
| ▸ | CCNE1 | P24864 | 6/20 | 0.48 |
| ▸ | CDK2 | P24941 | 6/20 | 0.48 |
| ▸ | CDK1 | P06493 | 3/20 | 0.38 |
| ▸ | FLT3 | P36888 | 4/20 | 0.35 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.31 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
| ▸ | HTR2C | P28335 | 1/20 | 0.30 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6203387 | 0.90 | CCNE2 (0.38) | CCNE2CCNE1CDK2CDK1CDK5 | |
| SCHEMBL6206198 | 0.83 | CCNE2 (0.46) | CCNE2CCNE1CDK2CDK1FLT3 | |
| SCHEMBL6205532 | 0.83 | CDK5 (0.35) | CCNE2CCNE1CDK2CDK1CDK5 | |
| SCHEMBL6202790 | 0.83 | CDK5 (0.35) | CCNE2CCNE1CDK2CDK1CDK5 | |
| SCHEMBL6206176 | 0.83 | CDK5 (0.49) | CCNE2CCNE1CDK2CDK1CDK5 | |
| SCHEMBL6202658 | 0.82 | CDK1 (0.44) | CCNE2CCNE1CDK2CDK1CDK5 | |
| SCHEMBL6205009 | 0.81 | CDK5 (0.44) | CCNE2CCNE1CDK2CDK1CDK5 | |
| SCHEMBL6203872 | 0.81 | CDK1 (0.44) | CCNE2CCNE1CDK2CDK1CDK5 | |
| SCHEMBL6204662 | 0.81 | CLK1 (0.41) | CCNE2CCNE1CDK2CDK1CDK5 | |
| SCHEMBL6201113 | 0.78 | CDK1 (0.46) | CCNE2CCNE1CDK2CDK1CDK5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1539760-A2 | AZAPURINE DERIVATIVES | INSTITUTE OF EXPERIMENTAL BOTANY ASCR (CZ) | 2005-06-15 | — | — | EP | disclosed |
| WO-2004018473-A2 | AZAPURINE DERIVATIVES | INSTITUTE OF EXPERIMENTAL BOTANY ASCR (CZ) | 2004-03-04 | — | — | WO | disclosed |