Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNE2 | O96020 | 4/20 | 0.38 |
| ▸ | CCNE1 | P24864 | 4/20 | 0.38 |
| ▸ | CDK2 | P24941 | 4/20 | 0.38 |
| ▸ | CDK1 | P06493 | 1/20 | 0.38 |
| ▸ | HTR2C | P28335 | 2/20 | 0.37 |
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.36 |
| ▸ | P2RX3 | P56373 | 5/20 | 0.34 |
| ▸ | CCR4 | P51679 | 1/20 | 0.32 |
| ▸ | TACR2 | P21452 | 3/20 | 0.32 |
| ▸ | CRHR1 | P34998 | 1/20 | 0.31 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6202083 | 0.90 | CCNE2 (0.48) | CCNE2CCNE1CDK2CDK1HTR2C | |
| SCHEMBL6206176 | 0.89 | CDK5 (0.49) | CCNE2CCNE1CDK2CDK1HTR2C | |
| SCHEMBL6202790 | 0.87 | CDK5 (0.35) | CCNE2CCNE1CDK2CDK1CDK5 | |
| SCHEMBL6205532 | 0.87 | CDK5 (0.35) | CCNE2CCNE1CDK2CDK1CDK5 | |
| SCHEMBL6204662 | 0.87 | CLK1 (0.41) | CCNE2CCNE1CDK2CDK1CDK5 | |
| SCHEMBL6203872 | 0.85 | CDK1 (0.44) | CCNE2CCNE1CDK2CDK1CDK5 | |
| SCHEMBL6205009 | 0.85 | CDK5 (0.44) | CCNE2CCNE1CDK2CDK1CDK5 | |
| SCHEMBL6202658 | 0.82 | CDK1 (0.44) | CCNE2CCNE1CDK2CDK1CDK5 | |
| SCHEMBL6201113 | 0.78 | CDK1 (0.46) | CCNE2CCNE1CDK2CDK1CDK5 | |
| SCHEMBL6203391 | 0.78 | CCNE2 (0.31) | CCNE2CCNE1CDK2CDK1CDK5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1539760-A2 | AZAPURINE DERIVATIVES | INSTITUTE OF EXPERIMENTAL BOTANY ASCR (CZ) | 2005-06-15 | — | — | EP | claimed |
| WO-2004018473-A2 | AZAPURINE DERIVATIVES | INSTITUTE OF EXPERIMENTAL BOTANY ASCR (CZ) | 2004-03-04 | — | — | WO | claimed |
| EP-1539760-A2 | AZAPURINE DERIVATIVES | INSTITUTE OF EXPERIMENTAL BOTANY ASCR (CZ) | 2005-06-15 | — | — | EP | disclosed |
| WO-2004018473-A2 | AZAPURINE DERIVATIVES | INSTITUTE OF EXPERIMENTAL BOTANY ASCR (CZ) | 2004-03-04 | — | — | WO | disclosed |