Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK5 | Q00535 | 3/20 | 0.35 |
| ▸ | CDK5R1 | Q15078 | 3/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | CCNE2 | O96020 | 4/20 | 0.33 |
| ▸ | CCNE1 | P24864 | 4/20 | 0.33 |
| ▸ | CDK2 | P24941 | 4/20 | 0.33 |
| ▸ | CDK1 | P06493 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6202790 | 0.93 | CDK5 (0.35) | CDK5CDK5R1ATMCCNE2CCNE1 | |
| SCHEMBL6203872 | 0.87 | CDK1 (0.44) | CDK5CDK5R1ATMCCNE2CCNE1 | |
| SCHEMBL6203387 | 0.87 | CCNE2 (0.38) | CDK5CDK5R1ATMCCNE2CCNE1 | |
| SCHEMBL6205538 | 0.86 | CCNE2 (0.35) | CDK5CDK5R1CCNE2CCNE1CDK2 | |
| SCHEMBL6206176 | 0.85 | CDK5 (0.49) | CDK5CDK5R1ATMCCNE2CCNE1 | |
| SCHEMBL6204662 | 0.85 | CLK1 (0.41) | CDK5CDK5R1ATMCCNE2CCNE1 | |
| SCHEMBL6205009 | 0.85 | CDK5 (0.44) | CDK5CDK5R1ATMCCNE2CCNE1 | |
| SCHEMBL6202083 | 0.83 | CCNE2 (0.48) | CDK5CDK5R1ATMCCNE2CCNE1 | |
| SCHEMBL6202658 | 0.81 | CDK1 (0.44) | CDK5CDK5R1ATMCCNE2CCNE1 | |
| SCHEMBL3445562 | 0.79 | CDK5 (0.47) | CDK5CDK5R1CCNE2CCNE1CDK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1539760-A2 | AZAPURINE DERIVATIVES | INSTITUTE OF EXPERIMENTAL BOTANY ASCR (CZ) | 2005-06-15 | — | — | EP | claimed |
| WO-2004018473-A2 | AZAPURINE DERIVATIVES | INSTITUTE OF EXPERIMENTAL BOTANY ASCR (CZ) | 2004-03-04 | — | — | WO | claimed |