Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | PPARG | P37231 | 4/20 | 0.43 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.43 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | RXRA | P19793 | 1/20 | 0.43 |
| ▸ | OXER1 | Q8TDS5 | 1/20 | 0.43 |
| ▸ | BLM | P54132 | 3/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.39 |
| ▸ | GMNN | O75496 | 2/20 | 0.39 |
| ▸ | USP2 | O75604 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.39 |
| ▸ | APEX1 | P27695 | 2/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.39 |
| ▸ | RECQL | P46063 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19114920 | 0.83 | MAPT (0.55) | MAPTPPARGCYP19A1ALDH1A1OXER1 | |
| SCHEMBL7394391 | 0.83 | GMNN (0.32) | MAPTPPARGCYP19A1FFAR1ALDH1A1 | |
| SCHEMBL18992838 | 0.83 | MAPT (0.55) | MAPTPPARGCYP19A1ALDH1A1OXER1 | |
| SCHEMBL4614060 | 0.77 | THRB (0.39) | MAPTPPARGCYP19A1FFAR1ALDH1A1 | |
| SCHEMBL4614062 | 0.77 | THRB (0.39) | MAPTPPARGCYP19A1FFAR1ALDH1A1 | |
| SCHEMBL5420623 | 0.76 | PPARG (0.48) | MAPTPPARGCYP19A1FFAR1ALDH1A1 | |
| SCHEMBL176452 | 0.76 | PPARG (0.64) | MAPTPPARGCYP19A1FFAR1ALDH1A1 | |
| SCHEMBL176453 | 0.76 | PPARG (0.64) | MAPTPPARGCYP19A1FFAR1ALDH1A1 | |
| SCHEMBL2540034 | 0.76 | PPARG (0.64) | MAPTPPARGCYP19A1FFAR1ALDH1A1 | |
| SCHEMBL6202148 | 0.75 | ALDH1A1 (0.55) | ALDH1A1CYP2D6ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1501877-A1 | FLUORINATED POLYMERS | Honeywell International Inc. (US) | 2005-02-02 | — | — | EP | claimed |
| WO-2003095505-A1 | FLUORINATED POLYMERS | HONEYWELL INTERNATIONAL INC. (US) | 2003-11-20 | — | — | WO | claimed |