Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABL1 | P00519 | 1/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.52 |
| ▸ | GLA | P06280 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | FLT1 | P17948 | 1/20 | 0.51 |
| ▸ | FLT4 | P35916 | 1/20 | 0.51 |
| ▸ | KDR | P35968 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.50 |
| ▸ | TSHR | P16473 | 3/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.50 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | CASP1 | P29466 | 2/20 | 0.47 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL128885 | 0.83 | SMN1; SMN2 (0.63) | ABL1ALDH1A1KDM4EGAAFLT1 | |
| SCHEMBL620233 | 0.83 | RECQL (0.59) | ABL1ALDH1A1KDM4EGLAGAA | |
| SCHEMBL3790275 | 0.82 | ALDH1A1 (0.60) | ABL1ALDH1A1KDM4EGLAGAA | |
| SCHEMBL28303002 | 0.81 | SMN1; SMN2 (0.61) | ABL1ALDH1A1KDM4EGAAFLT1 | |
| Hydrochloric Acid SCHEMBL8012538 | 0.81 | RECQL (0.58) | ABL1ALDH1A1KDM4EGLAGAA | |
| Ammonia Solution, Strong SCHEMBL2319232 | 0.81 | SMN1; SMN2 (0.61) | ABL1ALDH1A1KDM4EGAAFLT1 | |
| SCHEMBL400044 | 0.81 | ABL1 (0.65) | ABL1ALDH1A1KDM4EFLT1FLT4 | |
| Hydrochloric Acid SCHEMBL6750016 | 0.81 | SMN1; SMN2 (0.61) | ABL1ALDH1A1KDM4EGAAFLT1 | |
| SCHEMBL29758053 | 0.81 | ABL1 (0.65) | ABL1ALDH1A1KDM4EFLT1FLT4 | |
| SCHEMBL15597196 | 0.80 | ABL1 (0.54) | ABL1ALDH1A1KDM4EFLT1FLT4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 205 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117820337-A | Preparation method of 12H-benzo [4,5] thiazolo [2,3-b ] quinazoline 12-ketone compound | 赣南师范大学 | 2024-04-05 | — | — | CN | claimed |
| EP-4127157-B1 | MODIFIED DIPEPTIDE CLEAVASES, USES THEREOF AND RELATED KITS | ENCODIA INC (US) | 2026-02-11 | — | — | EP | disclosed |
| US-12503467-B2 | 2-oxoquinazoline derivatives as methionine adenosyltransferase 2A inhibitors | IDEAYA BIOSCIENCES, INC. (US) | 2025-12-23 | — | — | US | disclosed |
| US-12421222-B2 | Substituted quinazolines as HDAC6 inhibitors | AUGUSTINE THERAPEUTICS (BE) | 2025-09-23 | — | — | US | disclosed |
| US-20250145604-A1 | COMPOUNDS AND USE THEREOF AS HDAC6 INHIBITORS | AUGUSTINE THERAPEUTICS (BE) | 2025-05-08 | — | — | US | disclosed |
| CN-119528824-A | 2-Oxo quinazoline derivatives as methionine adenosyltransferase 2A inhibitors | 伊迪亚生物科学有限公司 | 2025-02-28 | — | — | CN | disclosed |
| US-20250051319-A1 | COMPOUNDS AND USE THEREOF AS HDAC6 INHIBITORS | AUGUSTINE THERAPEUTICS (BE) | 2025-02-13 | — | — | US | disclosed |
| CN-119019339-A | Preparation method of quinazolinone compound promoted by mercaptan without catalyst | 南京化纤股份有限公司 | 2024-11-26 | — | — | CN | disclosed |
| CN-113166078-B | 2-Oxo quinazoline derivatives as methionine adenosyltransferase 2A inhibitors | 伊迪亚生物科学有限公司 | 2024-11-19 | — | — | CN | disclosed |
| EP-4452265-A2 | COMPOUNDS AND USE THEREOF AS HDAC6 INHIBITORS | Augustine Therapeutics (BE) | 2024-10-30 | — | — | EP | disclosed |
| US-5187168-A | Hypotensive agents | AMERICAN HOME PRODUCTS CORPORATION (US) | 1993-02-16 | — | — | US | disclosed |
| US-5066577-A | Colorfast cyan dye for diffusion transfer photography process | FUJI PHOTO FILM CO., LTD. (JP) | 1991-11-19 | — | — | US | disclosed |
| EP-0401612-A2 | Colour photographic recording material with a DIR coupler | Agfa-Gevaert AG (DE) | 1990-12-12 | — | — | EP | disclosed |
| EP-0394943-A2 | Silver halide color photographic material | FUJI PHOTO FILM CO., LTD. (JP) | 1990-10-31 | — | — | EP | disclosed |
| US-4400507-A | FOR COLORING POLYMERS, LACQUERS | CIBA-GEIGY CORPORATION (US) | 1983-08-23 | — | — | US | disclosed |
| EP-0009608-B1 | N-PHENETHYLACETAMIDE COMPOUNDS, PROCESSES FOR THEIR PREPARATION AND THERAPEUTIC COMPOSITIONS CONTAINING THEM | DAIICHI SEIYAKU CO., LTD. (JP) | 1982-04-21 | — | — | EP | disclosed |
| US-4307113-A | TREATMENT OF DIABETES | SANDOZ, INC. (US) | 1981-12-22 | — | — | US | disclosed |
| US-4297357-A | ANTIULCER AGENTS; ANTISECRETORY AGENTS | DAIICHI SEIYAKU CO., LTD. (JP) | 1981-10-27 | — | — | US | disclosed |
| US-4262120-A | YELLOW TO ORANGE SHADES OF GOOD FASTNESS | CIBA-GEIGY CORPORATION (US) | 1981-04-14 | — | — | US | disclosed |
| EP-0009608-A1 | N-Phenethylacetamide compounds, processes for their preparation and therapeutic compositions containing them | DAIICHI SEIYAKU CO., LTD. (JP) | 1980-04-16 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250051319-A1 | COMPOUNDS AND USE THEREOF AS HDAC6 INHIBITORS | HDAC6, HDAC9, HDAC1 | ABL1 926/4885ALDH1A1 608/4885KDM4E 2750/4885 |
| US-20250145604-A1 | COMPOUNDS AND USE THEREOF AS HDAC6 INHIBITORS | HDAC6, HDAC9, HDAC1 | ABL1 926/4885ALDH1A1 608/4885KDM4E 2750/4885 |
| US-12421222-B2 | Substituted quinazolines as HDAC6 inhibitors | HDAC6, HDAC9, HDAC1 | ABL1 518/4885ALDH1A1 850/4885KDM4E 3008/4885 |
| US-12503467-B2 | 2-oxoquinazoline derivatives as methionine adenosyltransferase 2A inhibitors | MAT2B, MAT2A, MAT1A | ABL1 2182/4885ALDH1A1 910/4885KDM4E 1484/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.