Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | CDK2 | P24941 | 6/20 | 0.35 |
| ▸ | CCNE1 | P24864 | 5/20 | 0.35 |
| ▸ | CDK5 | Q00535 | 4/20 | 0.35 |
| ▸ | CDK5R1 | Q15078 | 4/20 | 0.35 |
| ▸ | CCNT1 | O60563 | 3/20 | 0.35 |
| ▸ | CDK9 | P50750 | 3/20 | 0.35 |
| ▸ | CDK1 | P06493 | 6/20 | 0.34 |
| ▸ | CCNB2 | O95067 | 4/20 | 0.34 |
| ▸ | CCNB1 | P14635 | 4/20 | 0.34 |
| ▸ | CCNB3 | Q8WWL7 | 4/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | F2 | P00734 | 1/20 | 0.34 |
| ▸ | PDE8B | O95263 | 1/20 | 0.34 |
| ▸ | CDK7 | P50613 | 1/20 | 0.33 |
| ▸ | CCNH | P51946 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6201910 | 0.83 | ALDH1A1 (0.49) | ALDH1A1LMNASMN1; SMN2KMT2ACDK2 | |
| SCHEMBL6226169 | 0.80 | KMT2A (0.56) | ALDH1A1LMNASMN1; SMN2KMT2ACDK2 | |
| SCHEMBL6203832 | 0.80 | KMT2A (0.46) | ALDH1A1LMNASMN1; SMN2KMT2ACDK2 | |
| SCHEMBL6204206 | 0.75 | CCNE1 (0.42) | ALDH1A1LMNASMN1; SMN2KMT2ACDK2 | |
| SCHEMBL3443923 | 0.72 | CDK2 (0.48) | ALDH1A1SMN1; SMN2KMT2ACDK2CCNE1 | |
| SCHEMBL6203399 | 0.72 | KMT2A (0.42) | ALDH1A1LMNASMN1; SMN2KMT2ACDK2 | |
| SCHEMBL3446366 | 0.71 | CDK2 (0.46) | CDK2CCNE1CDK5CDK5R1CCNT1 | |
| SCHEMBL3445015 | 0.70 | CDK2 (0.43) | ALDH1A1CDK2CCNE1CDK5CDK5R1 | |
| SCHEMBL3446344 | 0.69 | CDK1 (0.52) | CDK2CCNE1CDK5CDK5R1CCNT1 | |
| SCHEMBL3446341 | 0.69 | CDK1 (0.52) | CDK2CCNE1CDK5CDK5R1CCNT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1539760-A2 | AZAPURINE DERIVATIVES | INSTITUTE OF EXPERIMENTAL BOTANY ASCR (CZ) | 2005-06-15 | — | — | EP | claimed |
| WO-2004018473-A2 | AZAPURINE DERIVATIVES | INSTITUTE OF EXPERIMENTAL BOTANY ASCR (CZ) | 2004-03-04 | — | — | WO | claimed |