Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LCK | P06239 | 1/20 | 0.30 |
| ▸ | BTK | Q06187 | 1/20 | 0.30 |
| ▸ | CDK1 | P06493 | 1/20 | 0.30 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.30 |
| ▸ | CCNE2 | O96020 | 1/20 | 0.30 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.30 |
| ▸ | CDK2 | P24941 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6203326 | 0.85 | CDK2 (0.38) | CDK1CDK5CCNE2CCNE1CDK2 | |
| SCHEMBL6204524 | 0.84 | CCNE2 (0.34) | CDK1CDK5CCNE2CCNE1CDK2 | |
| SCHEMBL6205469 | 0.82 | — | — | |
| SCHEMBL6201142 | 0.81 | CDK1 (0.46) | CDK1CDK5CCNE2CCNE1CDK2 | |
| SCHEMBL6204274 | 0.80 | CCR4 (0.33) | CCNE2CCNE1CDK2 | |
| SCHEMBL6204246 | 0.78 | BRAF (0.35) | CDK5CCNE2CCNE1CDK2 | |
| SCHEMBL6204587 | 0.78 | BRAF (0.35) | CDK5CCNE2CCNE1CDK2 | |
| SCHEMBL3445251 | 0.78 | CDK2 (0.44) | LCKBTKCDK1CDK5CCNE1 | |
| SCHEMBL3445230 | 0.78 | CDK2 (0.40) | CDK1CDK5CCNE2CCNE1CDK2 | |
| SCHEMBL6203788 | 0.77 | CCNE2 (0.32) | CDK1CDK5CCNE2CCNE1CDK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1539760-A2 | AZAPURINE DERIVATIVES | INSTITUTE OF EXPERIMENTAL BOTANY ASCR (CZ) | 2005-06-15 | — | — | EP | disclosed |
| WO-2004018473-A2 | AZAPURINE DERIVATIVES | INSTITUTE OF EXPERIMENTAL BOTANY ASCR (CZ) | 2004-03-04 | — | — | WO | disclosed |