Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNE2 | O96020 | 8/20 | 0.34 |
| ▸ | CCNE1 | P24864 | 8/20 | 0.34 |
| ▸ | CDK2 | P24941 | 8/20 | 0.34 |
| ▸ | PDE5A | O76074 | 4/20 | 0.34 |
| ▸ | PDE4D | Q08499 | 3/20 | 0.34 |
| ▸ | PDE6C | P51160 | 2/20 | 0.34 |
| ▸ | CDK1 | P06493 | 3/20 | 0.33 |
| ▸ | CDK5 | Q00535 | 2/20 | 0.33 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.33 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.33 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.33 |
| ▸ | CDK7 | P50613 | 1/20 | 0.33 |
| ▸ | CDK9 | P50750 | 1/20 | 0.33 |
| ▸ | CCNH | P51946 | 1/20 | 0.33 |
| ▸ | MNAT1 | P51948 | 1/20 | 0.33 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.33 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.33 |
| ▸ | PRUNE1 | Q86TP1 | 1/20 | 0.32 |
| ▸ | CCNK | O75909 | 1/20 | 0.31 |
| ▸ | CDK12 | Q9NYV4 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6204246 | 0.85 | BRAF (0.35) | CCNE2CCNE1CDK2CDK5CDK5R1 | |
| SCHEMBL6202508 | 0.84 | LCK (0.30) | CCNE2CCNE1CDK2CDK1CDK5 | |
| SCHEMBL6201142 | 0.83 | CDK1 (0.46) | CCNE2CCNE1CDK2PDE5APDE4D | |
| SCHEMBL6204274 | 0.82 | CCR4 (0.33) | CCNE2CCNE1CDK2 | |
| SCHEMBL6203326 | 0.81 | CDK2 (0.38) | CCNE2CCNE1CDK2PDE5APDE4D | |
| SCHEMBL6205469 | 0.81 | — | — | |
| SCHEMBL6204587 | 0.80 | BRAF (0.35) | CCNE2CCNE1CDK2CDK5CDK5R1 | |
| SCHEMBL6203806 | 0.80 | STAT3 (0.36) | CCNE2CCNE1CDK2PDE5APDE4D | |
| SCHEMBL3445349 | 0.78 | CDK2 (0.42) | CCNE1CDK2CDK1CDK5CDK7 | |
| SCHEMBL6205328 | 0.78 | PARP1 (0.36) | CCNE2CCNE1CDK2PDE5APDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1539760-A2 | AZAPURINE DERIVATIVES | INSTITUTE OF EXPERIMENTAL BOTANY ASCR (CZ) | 2005-06-15 | — | — | EP | claimed |
| WO-2004018473-A2 | AZAPURINE DERIVATIVES | INSTITUTE OF EXPERIMENTAL BOTANY ASCR (CZ) | 2004-03-04 | — | — | WO | claimed |