Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGKA | P23743 | 1/20 | 0.45 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.39 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.39 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | BLM | P54132 | 1/20 | 0.38 |
| ▸ | HTR2C | P28335 | 1/20 | 0.37 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.37 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.37 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.37 |
| ▸ | NAAA | Q02083 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.35 |
| ▸ | TOP2A | P11388 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3904302 | 0.81 | NAAA (0.38) | DGKAALDH1A1PRSS1PRSS2PRSS3 | |
| SCHEMBL20589 | 0.79 | DGKA (0.58) | DGKAADRA2AADRA1ADNM1ALDH1A1 | |
| SCHEMBL21618267 | 0.78 | DGKA (0.52) | DGKAADRA2AADRA1ADNM1ALDH1A1 | |
| SCHEMBL125157 | 0.77 | — | — | |
| SCHEMBL8851174 | 0.77 | DGKA (0.47) | DGKAADRA2AADRA1ADNM1ALDH1A1 | |
| SCHEMBL141329 | 0.76 | DGKA (0.50) | DGKAADRA2AADRA1ADNM1ALDH1A1 | |
| SCHEMBL443342 | 0.76 | DGKA (0.50) | DGKAADRA2AADRA1ADNM1ALDH1A1 | |
| SCHEMBL11321566 | 0.75 | DGKA (0.45) | DGKAADRA2AADRA1ADNM1ALDH1A1 | |
| SCHEMBL19638 | 0.75 | DGKA (0.67) | DGKAADRA2AADRA1ADNM1ALDH1A1 | |
| SCHEMBL31355082 | 0.75 | ALDH1A1 (0.55) | DGKAADRA2AADRA1ADNM1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1503994-A1 | SUBSTITUTED (THIOXO)CARBONYLAMINO PHENYL URACILES | Bayer CropScience AG (DE) | 2005-02-09 | — | — | EP | disclosed |
| WO-2003093244-A1 | SUBSTITUTED (THIOXO)CARBONYLAMINO PHENYL URACILES | BAYER CROPSCIENCE AG (DE) | 2003-11-13 | — | — | WO | disclosed |