Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.56 |
| ▸ | MAPT | P10636 | 2/20 | 0.56 |
| ▸ | RAB9A | P51151 | 3/20 | 0.54 |
| ▸ | NPC1 | O15118 | 2/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | ATM | Q13315 | 1/20 | 0.52 |
| ▸ | FLT1 | P17948 | 1/20 | 0.50 |
| ▸ | FLT4 | P35916 | 1/20 | 0.50 |
| ▸ | KDR | P35968 | 1/20 | 0.50 |
| ▸ | THRB | P10828 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.47 |
| ▸ | PARP1 | P09874 | 1/20 | 0.47 |
| ▸ | EGFR | P00533 | 1/20 | 0.47 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.47 |
| ▸ | CNR1 | P21554 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27626615 | 0.88 | PARP1 (0.52) | L3MBTL1MAPTRAB9ANPC1MEN1 | |
| SCHEMBL931177 | 0.85 | MAPT (0.57) | L3MBTL1MAPTRAB9ANPC1MEN1 | |
| SCHEMBL4183610 | 0.81 | MAPT (0.51) | L3MBTL1MAPTRAB9ANPC1MEN1 | |
| SCHEMBL1845879 | 0.81 | MAPT (0.49) | L3MBTL1MAPTRAB9ANPC1MEN1 | |
| SCHEMBL6204433 | 0.80 | MAPT (0.54) | MAPTRAB9ANPC1ATMMEN1 | |
| SCHEMBL6201625 | 0.80 | RAB9A (0.71) | L3MBTL1MAPTRAB9ANPC1MEN1 | |
| SCHEMBL5318356 | 0.80 | RAB9A (0.71) | L3MBTL1MAPTRAB9ANPC1MEN1 | |
| SCHEMBL571046 | 0.79 | L3MBTL1 (0.85) | L3MBTL1MAPTRAB9ANPC1POLB | |
| SCHEMBL28872875 | 0.79 | MAPT (0.65) | L3MBTL1MAPTRAB9AMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL28260371 | 0.78 | L3MBTL1 (0.82) | L3MBTL1MAPTRAB9ANPC1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050272036-A1 | Ketones | ASTRAZENECA AB (SE) | 2005-12-08 | — | — | US | disclosed |
| CN-1681763-A | Chemical compounds | ASTRAZENECA AB (SE) | 2005-10-12 | — | — | CN | disclosed |
| EP-1549600-A1 | KETONES | AstraZeneca AB (SE) | 2005-07-06 | — | — | EP | disclosed |
| WO-2004011410-A1 | CHEMICAL COMPOUNDS | ASTRAZENECA AB (SE) | 2004-02-05 | — | — | WO | disclosed |