Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | NOX1 | Q9Y5S8 | 1/20 | 0.39 |
| ▸ | PABPC1 | P11940 | 2/20 | 0.38 |
| ▸ | APOBEC3A | P31941 | 2/20 | 0.38 |
| ▸ | EIF4H | Q15056 | 2/20 | 0.38 |
| ▸ | APOBEC3G | Q9HC16 | 2/20 | 0.38 |
| ▸ | BCHE | P06276 | 3/20 | 0.37 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.35 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6200358 | 0.83 | MAPT (0.36) | LMNAMEN1KMT2AGAAALDH1A1 | |
| SCHEMBL5418077 | 0.82 | ALDH1A1 (0.51) | LMNAMEN1KMT2AGAAALDH1A1 | |
| SCHEMBL6204224 | 0.79 | TYMS (0.37) | MEN1KMT2AGAAALDH1A1TDP1 | |
| SCHEMBL9257995 | 0.71 | KMT2A (0.45) | LMNAMEN1KMT2AGAAALDH1A1 | |
| SCHEMBL5418030 | 0.71 | CYP2A6 (0.41) | GAAALDH1A1MAPTNOX1BCHE | |
| SCHEMBL5252071 | 0.68 | BCHE (0.43) | LMNAMEN1KMT2AGAAALDH1A1 | |
| SCHEMBL4047340 | 0.68 | PPARG (0.44) | LMNAMEN1KMT2AALDH1A1L3MBTL1 | |
| SCHEMBL6204171 | 0.68 | ALDH1A1 (0.38) | GAAALDH1A1TDP1HSD17B10MAPT | |
| SCHEMBL4043160 | 0.67 | PPARG (0.43) | LMNAMEN1KMT2AALDH1A1L3MBTL1 | |
| SCHEMBL5771136 | 0.67 | BCHE (0.42) | LMNAMEN1KMT2AGAAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1492795-B1 | 1- OR 3-THIA-BENZONAPHTHOAZULENES AS INHIBITORS OF TUMOUR NECROSIS FACTOR PRODUCTION AND INTERMEDIATES FOR THE PREPARATION THEREOF | PLIVA ISTRAZIVACKI INST D O O (HR) | 2005-11-16 | — | — | EP | claimed |