Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 6/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.57 |
| ▸ | BCHE | P06276 | 3/20 | 0.52 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.52 |
| ▸ | MAOA | P21397 | 1/20 | 0.51 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.51 |
| ▸ | SGMS2 | Q8NHU3 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.49 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.49 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.47 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6203969 | 0.84 | MAOB (0.63) | MAOBKMT2ASMN1; SMN2BCHEALOX5 | |
| SCHEMBL6204242 | 0.83 | LMNA (0.53) | MAOBSMN1; SMN2ALOX5MAOANR4A2 | |
| SCHEMBL6202972 | 0.82 | MAOB (0.59) | MAOBKMT2ASMN1; SMN2BCHEALOX5 | |
| SCHEMBL27733470 | 0.81 | MAOB (0.58) | MAOBKMT2ASMN1; SMN2BCHEALOX5 | |
| SCHEMBL3653833 | 0.81 | MAOB (0.55) | MAOBKMT2ASMN1; SMN2BCHEALOX5 | |
| SCHEMBL5038222 | 0.81 | KMT2A (0.60) | MAOBKMT2ASMN1; SMN2BCHEALOX5 | |
| SCHEMBL903792 | 0.81 | MAOB (0.62) | MAOBKMT2ASMN1; SMN2BCHEALOX5 | |
| SCHEMBL684282 | 0.81 | MAOB (0.62) | MAOBKMT2ASMN1; SMN2BCHEALOX5 | |
| SCHEMBL6204182 | 0.81 | TP53 (0.49) | KMT2ASMN1; SMN2MEN1 | |
| Formaldehyde SCHEMBL27575662 | 0.80 | KMT2A (0.58) | MAOBKMT2ASMN1; SMN2BCHEALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1668601-A | N-substituted tricyclic 3-aminopyrazoles as PDFG receptor inhibitors | JANSSEN PHARMACEUTICA NV (BE) | 2005-09-14 | — | — | CN | disclosed |
| EP-1506175-A1 | N-SUBSTITUTED TRICYCLIC 3-AMINOPYRAZOLES AS PDGF RECEPTOR INHIBITORS | JANSSEN PHARMACEUTICA N.V. (BE) | 2005-02-16 | — | — | EP | disclosed |
| WO-2003097609-A1 | N-SUBSTITUTED TRICYCLIC 3-AMINOPYRAZOLES AS PDFG RECEPTOR INHIBITORS | JANSSEN PHARMACEUTICA N.V. (BE) | 2003-11-27 | — | — | WO | disclosed |