Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 2/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.49 |
| ▸ | HPGD | P15428 | 4/20 | 0.49 |
| ▸ | GAA | P10253 | 3/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 3/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6203082 | 0.87 | HSD17B10 (0.56) | FAAHHSD17B10KDM4EHPGDGAA | |
| SCHEMBL6203549 | 0.79 | SMN1; SMN2 (0.52) | FAAHHSD17B10KDM4EHPGDGAA | |
| SCHEMBL6202061 | 0.79 | FAAH (0.58) | FAAHHSD17B10KDM4EHPGDGAA | |
| SCHEMBL6203431 | 0.76 | GAA (0.60) | FAAHHSD17B10KDM4EHPGDGAA | |
| SCHEMBL6085080 | 0.75 | MAPT (0.49) | HSD17B10KDM4EHPGDNPSR1SMN1; SMN2 | |
| SCHEMBL6201149 | 0.74 | GAA (0.54) | FAAHHSD17B10KDM4EHPGDGAA | |
| SCHEMBL6203914 | 0.74 | KDM4E (0.52) | FAAHHSD17B10KDM4EHPGDGAA | |
| SCHEMBL6200946 | 0.74 | PKM (0.54) | FAAHHSD17B10KDM4EHPGDGAA | |
| SCHEMBL6200627 | 0.71 | HSD17B10 (0.48) | FAAHHSD17B10KDM4EHPGDGAA | |
| SCHEMBL6203580 | 0.70 | HSD17B10 (0.48) | FAAHHSD17B10KDM4EHPGDGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1377589-B1 | OXAZOLYL-PYRAZOLE DERIVATIVES AS KINASE INHIBITORS | PHARMACIA ITALIA SPA (IT) | 2005-09-07 | — | — | EP | claimed |