Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 3/20 | 0.45 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.45 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.45 |
| ▸ | TSHR | P16473 | 3/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | MMP2 | P08253 | 1/20 | 0.37 |
| ▸ | CA9 | Q16790 | 1/20 | 0.37 |
| ▸ | ABL1 | P00519 | 1/20 | 0.36 |
| ▸ | SRC | P12931 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11620549 | 0.94 | SLC6A3 (0.42) | SLC6A2SLC6A4SLC6A3TSHRMAPK1 | |
| SCHEMBL28824086 | 0.88 | NPC1 (0.42) | SLC6A2SLC6A4SLC6A3SMN1; SMN2HPGD | |
| SCHEMBL6679840 | 0.87 | TSHR (0.44) | SLC6A2SLC6A4SLC6A3TSHRMAPK1 | |
| SCHEMBL8973155 | 0.83 | HRH3 (0.45) | SLC6A2SLC6A4SLC6A3TDP1SMN1; SMN2 | |
| SCHEMBL28429634 | 0.82 | HTR7 (0.39) | SLC6A2SLC6A4SLC6A3MAPK1SMN1; SMN2 | |
| SCHEMBL27647959 | 0.82 | CYP1A2 (0.37) | MAPK1TDP1SMN1; SMN2LMNAHPGD | |
| SCHEMBL11623007 | 0.82 | MMP2 (0.44) | SLC6A2SLC6A4SLC6A3TSHRMAPK1 | |
| SCHEMBL28771687 | 0.82 | BDKRB2 (0.40) | TSHRMAPK1TDP1SMN1; SMN2LMNA | |
| SCHEMBL9016030 | 0.82 | ESR1 (0.47) | SLC6A2SLC6A4SLC6A3HIF1ATDP1 | |
| SCHEMBL28017458 | 0.82 | MAPT (0.39) | SLC6A2SLC6A4SLC6A3TSHRMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011023791-A2 | METHOD FOR PRODUCING ORGANOALUMINIUM COMPOUNDS AND USE THEREOF | LUDWIG-MAXIMILIANS-UNIVERSITÄT MÜNCHEN (DE) | 2011-03-03 | — | — | WO | disclosed |
| EP-0410466-B1 | Substituted phenylalkylimidazole compounds | HODOGAYA CHEMICAL CO LTD (JP) | 1996-04-03 | — | — | EP | disclosed |
| US-5057145-A | PHENYLALKYLIMIDAZOLE COMPOUNDS AS FUNGICIDES | HODOGAYA CHEMICAL CO., LTD. (JP) | 1991-10-15 | — | — | US | disclosed |
| EP-0410466-A2 | Substituted phenylalkylimidazole compounds | HODOGAYA CHEMICAL CO., LTD. (JP) | 1991-01-30 | — | — | EP | disclosed |