Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | CHKA | P35790 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.31 |
| ▸ | PARP1 | P09874 | 1/20 | 0.31 |
| ▸ | CTSK | P43235 | 1/20 | 0.31 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16673827 | 0.93 | CA2 (0.32) | CA2CHKAPARP1CTSKUSP2 | |
| SCHEMBL106664 | 0.93 | USP2 (0.34) | CA2CHKAHPGDPARP1CTSK | |
| SCHEMBL2373613 | 0.82 | HPGD (0.41) | HPGDEPHX1CTSKUSP2SMN1; SMN2 | |
| SCHEMBL4434089 | 0.80 | HPGD (0.39) | HPGDEPHX1CTSKUSP2SMN1; SMN2 | |
| SCHEMBL4046200 | 0.78 | L3MBTL3 (0.33) | HPGDPARP1SMN1; SMN2 | |
| SCHEMBL4594886 | 0.78 | GNAI3 (0.38) | — | |
| SCHEMBL11889891 | 0.78 | CYP1A2 (0.41) | — | |
| SCHEMBL4658596 | 0.76 | CHRM2 (0.33) | HPGDSIGMAR1 | |
| SCHEMBL28055961 | 0.76 | CA2 (0.33) | CA2CHKAHPGDSIGMAR1 | |
| SCHEMBL5875153 | 0.75 | CA2 (0.41) | CA2CHKASIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1381392-A4 | SYNTHETIC CATALYST FOR SELECTIVE CLEAVAGE OF PROTEIN AND METHOD FOR SELECTIVE CLEAVAGE OF PROTEIN USING THE SAME | TS CORP (KR) | 2005-03-23 | — | — | EP | disclosed |
| EP-1381392-A1 | SYNTHETIC CATALYST FOR SELECTIVE CLEAVAGE OF PROTEIN AND METHOD FOR SELECTIVE CLEAVAGE OF PROTEIN USING THE SAME | TS Corporation (KR) | 2004-01-21 | — | — | EP | disclosed |
| WO-2002085413-A1 | SYNTHETIC CATALYST FOR SELECTIVE CLEAVAGE OF PROTEIN AND METHOD FOR SELECTIVE CLEAVAGE OF PROTEIN USING THE SAME | TS CORPORATION (KR) | 2002-10-31 | — | — | WO | disclosed |