Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 2/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.33 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.33 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.33 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.33 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.32 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.32 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.32 |
| ▸ | CHRNB3 | Q05901 | 1/20 | 0.32 |
| ▸ | CHRNA6 | Q15825 | 1/20 | 0.32 |
| ▸ | PREP | P48147 | 1/20 | 0.31 |
| ▸ | PLAT | P00750 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4046200 | 0.90 | L3MBTL3 (0.33) | CHRM2CHRM1CHRM3L3MBTL3L3MBTL1 | |
| SCHEMBL27694570 | 0.86 | L3MBTL3 (0.34) | CHRM2CHRM1CHRM3L3MBTL3L3MBTL1 | |
| SCHEMBL4068290 | 0.84 | L3MBTL3 (0.36) | CHRM2CHRM1CHRM3L3MBTL3L3MBTL1 | |
| SCHEMBL16673574 | 0.84 | SIGMAR1 (0.38) | CHRM2CHRM1CHRM3L3MBTL3L3MBTL1 | |
| SCHEMBL4594886 | 0.83 | GNAI3 (0.38) | L3MBTL3L3MBTL1 | |
| SCHEMBL106664 | 0.82 | USP2 (0.34) | HPGDSIGMAR1CHRNB2CHRNA3CHRNA4 | |
| SCHEMBL27638301 | 0.79 | L3MBTL3 (0.32) | CHRM2CHRM1CHRM3L3MBTL3L3MBTL1 | |
| SCHEMBL4067285 | 0.79 | CHRM2 (0.36) | CHRM2CHRM1CHRM3HRH3PREP | |
| SCHEMBL118661 | 0.78 | HPGD (0.48) | L3MBTL1HPGDRECQLIRAK4 | |
| SCHEMBL4540435 | 0.78 | SMN1; SMN2 (0.33) | HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1917256-A2 | SELECTED CGRP ANTAGONISTS, METHODS FOR THE PRODUCTION THEREOF AND THEIR USE AS MEDICAMENTS | Boehringer Ingelheim International GmbH (DE) | 2008-05-07 | — | — | EP | disclosed |
| WO-2007020261-A2 | SELECTED CGRP ANTAGONISTS, METHODS FOR THE PRODUCTION THEREOF AND THEIR USE AS MEDICAMENTS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2007-02-22 | — | — | WO | disclosed |