Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6204673 | 0.80 | BTK (0.30) | BTK | |
| SCHEMBL6204157 | 0.80 | BTK (0.30) | BTK | |
| SCHEMBL6391548 | 0.78 | KMT2A (0.38) | KMT2A | |
| SCHEMBL6203394 | 0.76 | KMT2A (0.31) | KMT2A | |
| SCHEMBL4317287 | 0.75 | — | — | |
| SCHEMBL4318920 | 0.75 | — | — | |
| SCHEMBL6389427 | 0.74 | NPC1 (0.31) | KMT2A | |
| SCHEMBL6466403 | 0.72 | SHMT2 (0.33) | KMT2A | |
| SCHEMBL5948841 | 0.71 | PKM (0.30) | — | |
| SCHEMBL6273909 | 0.71 | TAS1R3 (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1511492-A2 | PROTEASE INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 2005-03-09 | — | — | EP | disclosed |
| WO-2003103574-A2 | PROTEASE INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 2003-12-18 | — | — | WO | disclosed |