Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | ACE | P12821 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6203392 | 0.76 | BTK (0.32) | KMT2A | |
| SCHEMBL6214073 | 0.68 | CTSK (0.42) | — | |
| SCHEMBL6592080 | 0.68 | PSEN1 (0.37) | KMT2A | |
| SCHEMBL7451825 | 0.67 | PSEN1 (0.36) | — | |
| SCHEMBL31207669 | 0.62 | POLB (0.44) | KMT2APOLB | |
| SCHEMBL7453888 | 0.60 | — | — | |
| SCHEMBL7447479 | 0.60 | — | — | |
| SCHEMBL25773882 | 0.60 | OPRM1 (0.36) | KMT2A | |
| SCHEMBL17893905 | 0.60 | BRD4 (0.39) | KMT2APOLB | |
| SCHEMBL20069720 | 0.60 | SMN1; SMN2 (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1511492-A2 | PROTEASE INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 2005-03-09 | — | — | EP | disclosed |
| WO-2003103574-A2 | PROTEASE INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 2003-12-18 | — | — | WO | disclosed |