Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | GPR88 | Q9GZN0 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 4/20 | 0.44 |
| ▸ | CA2 | P00918 | 4/20 | 0.44 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | CES2 | O00748 | 1/20 | 0.42 |
| ▸ | CES1 | P23141 | 1/20 | 0.42 |
| ▸ | PLK1 | P53350 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6202235 | 0.89 | SLC2A1 (0.45) | ALDH1A1SMN1; SMN2RAB9ANPC1GPR88 | |
| SCHEMBL6222701 | 0.84 | CA1 (0.47) | ALDH1A1SMN1; SMN2RAB9ANPC1CA1 | |
| SCHEMBL6323033 | 0.83 | TAS1R3 (0.45) | ALDH1A1SMN1; SMN2RAB9ANPC1GPR88 | |
| SCHEMBL6219820 | 0.78 | MAPT (0.48) | ALDH1A1SMN1; SMN2RAB9ANPC1GPR88 | |
| SCHEMBL6320430 | 0.77 | NPC1 (0.53) | ALDH1A1SMN1; SMN2RAB9ANPC1CA1 | |
| SCHEMBL22215186 | 0.76 | MDM2 (0.55) | ALDH1A1SMN1; SMN2RAB9ANPC1CA1 | |
| SCHEMBL2423154 | 0.75 | CES2 (0.53) | ALDH1A1SMN1; SMN2CA1CA2SLC2A1 | |
| SCHEMBL31432720 | 0.74 | TAS1R3 (0.60) | ALDH1A1SMN1; SMN2RAB9ANPC1CA1 | |
| SCHEMBL22017478 | 0.74 | TAS1R3 (0.60) | ALDH1A1SMN1; SMN2RAB9ANPC1CA1 | |
| SCHEMBL6539670 | 0.74 | ALDH1A1 (0.49) | ALDH1A1RAB9ANPC1CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050272036-A1 | Ketones | ASTRAZENECA AB (SE) | 2005-12-08 | — | — | US | disclosed |
| EP-1549600-A1 | KETONES | AstraZeneca AB (SE) | 2005-07-06 | — | — | EP | disclosed |
| WO-2004011410-A1 | CHEMICAL COMPOUNDS | ASTRAZENECA AB (SE) | 2004-02-05 | — | — | WO | disclosed |