Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6204671 | 0.88 | CRHR1 (0.49) | CRHR1CNR1 | |
| SCHEMBL6204591 | 0.88 | CRHR1 (0.43) | CRHR1CNR1 | |
| SCHEMBL6201596 | 0.88 | CRHR1 (0.48) | CRHR1CNR1 | |
| SCHEMBL6204028 | 0.88 | CRHR1 (0.48) | CRHR1CNR1 | |
| SCHEMBL6204093 | 0.87 | CRHR1 (0.42) | CRHR1CNR1 | |
| SCHEMBL6201218 | 0.87 | CRHR1 (0.42) | CRHR1CNR1 | |
| SCHEMBL5428233 | 0.82 | CRHR1 (0.59) | CRHR1 | |
| SCHEMBL4696905 | 0.81 | CRHR1 (0.41) | CRHR1CNR1 | |
| SCHEMBL7472124 | 0.80 | CRHR1 (0.53) | CRHR1CNR1 | |
| SCHEMBL7479379 | 0.80 | CRHR1 (0.57) | CRHR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1554258-A1 | 5-SUBSTITUTED-2-ARYLPYRAZINES AS MODULATORS OF CRF RECEPTORS | NEUROGEN CORPORATION (US) | 2005-07-20 | — | — | EP | claimed |
| WO-2004018437-A1 | 5-SUBSTITUTED-2-ARYLPYRAZINES AS MODULATORS OF CRF RECEPTORS | NEUROGEN CORPORATION (US) | 2004-03-04 | — | — | WO | claimed |