Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | GAA | P10253 | 2/20 | 0.32 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | ALPL | P05186 | 1/20 | 0.31 |
| ▸ | IDO1 | P14902 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | TTK | P33981 | 1/20 | 0.31 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.31 |
| ▸ | GPR3 | P46089 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2530675 | 0.71 | NISCH (0.46) | KDM4ECYP3A4ALDH1A1IDO1HPGD | |
| SCHEMBL6301542 | 0.71 | NPC1 (0.58) | KDM4EGAAALDH1A1HPGDHSD17B10 | |
| SCHEMBL1754216 | 0.70 | IDO1 (0.56) | KDM4EGAAPDPK1CYP3A4ALDH1A1 | |
| SCHEMBL2886575 | 0.70 | IDO1 (0.56) | KDM4EGAAPDPK1CYP3A4ALDH1A1 | |
| SCHEMBL7140034 | 0.70 | — | — | |
| SCHEMBL718222 | 0.70 | ALDH1A1 (0.41) | KDM4EGAAALDH1A1ALPLIDO1 | |
| SCHEMBL4309887 | 0.69 | PARP1 (0.36) | KDM4EGAAPDPK1CYP3A4ALDH1A1 | |
| SCHEMBL6608781 | 0.69 | MEN1 (0.31) | ALDH1A1GPR3HSD17B10 | |
| SCHEMBL4829952 | 0.69 | HSD17B10 (0.49) | KDM4EGAACYP3A4ALDH1A1HSD17B10 | |
| SCHEMBL6721218 | 0.68 | IMPDH2 (0.47) | KDM4EALDH1A1IDO1HPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1514942-A1 | METHOD OF SEARCHING SUBSTANE HAVING ANTIDIABETIC ACTIVITY | KYOWA HAKKO KOGYO CO., LTD. (JP) | 2005-03-16 | — | — | EP | disclosed |