Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 3/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.56 |
| ▸ | GAA | P10253 | 2/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.56 |
| ▸ | TTK | P33981 | 2/20 | 0.56 |
| ▸ | ALPL | P05186 | 1/20 | 0.56 |
| ▸ | HPGD | P15428 | 1/20 | 0.56 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.56 |
| ▸ | FGFR1 | P11362 | 2/20 | 0.54 |
| ▸ | FLT1 | P17948 | 2/20 | 0.54 |
| ▸ | LRRK2 | Q5S007 | 2/20 | 0.49 |
| ▸ | ITK | Q08881 | 5/20 | 0.46 |
| ▸ | AURKA | O14965 | 2/20 | 0.46 |
| ▸ | PDPK1 | O15530 | 2/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.45 |
| ▸ | MAP2K4 | P45985 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27956844 | 0.88 | IDO1 (0.61) | IDO1KDM4EGAAALDH1A1TTK | |
| SCHEMBL10692083 | 0.87 | KDM4E (0.59) | IDO1KDM4EGAAALDH1A1TTK | |
| SCHEMBL1672674 | 0.78 | IDO1 (0.78) | IDO1KDM4EGAAALDH1A1TTK | |
| SCHEMBL4220824 | 0.77 | AXL (0.49) | KDM4EGAAALDH1A1HPGDFGFR1 | |
| SCHEMBL6588566 | 0.76 | KDM4E (0.58) | IDO1KDM4EGAAALDH1A1TTK | |
| SCHEMBL2896639 | 0.75 | ITK (0.49) | TTKLRRK2ITKAURKAGRM4 | |
| SCHEMBL2885816 | 0.75 | LRRK2 (0.35) | IDO1KDM4EFGFR1FLT1LRRK2 | |
| SCHEMBL8365109 | 0.74 | MKNK1 (0.60) | IDO1KDM4EGAAALDH1A1TTK | |
| SCHEMBL855531 | 0.72 | ALDH1A1 (1.00) | IDO1KDM4EGAAALDH1A1TTK | |
| SCHEMBL30768403 | 0.72 | ALDH1A1 (1.00) | IDO1KDM4EGAAALDH1A1TTK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100113507-A1 | 3-Tetrazolyl Indazoles, 3-Tetrazolyl Pyrazolopyridines, and use Thereof | BAYER HEALTHCARE AG (DE) | 2010-05-06 | — | — | US | disclosed |
| US-20100113507-A1 | 3-Tetrazolyl Indazoles, 3-Tetrazolyl Pyrazolopyridines, and use Thereof | BAYER HEALTHCARE AG (DE) | 2010-05-06 | — | — | US | disclosed |
| US-20100113507-A1 | 3-Tetrazolyl Indazoles, 3-Tetrazolyl Pyrazolopyridines, and use Thereof | BAYER HEALTHCARE AG (DE) | 2010-05-06 | — | — | US | disclosed |
| EP-2024361-A1 | 3-TETRAZOLYL INDAZOLES, 3-TETRAZOLYL PYRAZOLOPYRIDINES, AND USE THEREOF | Bayer HealthCare AG (DE) | 2009-02-18 | — | — | EP | disclosed |
| EP-2024361-A1 | 3-TETRAZOLYL INDAZOLES, 3-TETRAZOLYL PYRAZOLOPYRIDINES, AND USE THEREOF | Bayer HealthCare AG (DE) | 2009-02-18 | — | — | EP | disclosed |
| WO-2007128454-A1 | 3-TETRAZOLYL INDAZOLES, 3-TETRAZOLYL PYRAZOLOPYRIDINES, AND USE THEREOF | BAYER HEALTHCARE AG (DE) | 2007-11-15 | — | — | WO | disclosed |
| WO-2007128454-A1 | 3-TETRAZOLYL INDAZOLES, 3-TETRAZOLYL PYRAZOLOPYRIDINES, AND USE THEREOF | BAYER HEALTHCARE AG (DE) | 2007-11-15 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100113507-A1 | 3-Tetrazolyl Indazoles, 3-Tetrazolyl Pyrazolopyridines, and use Thereof | TNNI3, FABP3, PPIP5K2 | IDO1 868/4885KDM4E 3980/4885GAA 2961/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.