Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 1/20 | 0.31 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL825251 | 0.79 | NOS3 (0.38) | LMNAL3MBTL1 | |
| SCHEMBL5968787 | 0.75 | L3MBTL1 (0.33) | GABRA1GABRB2LMNASMN1; SMN2L3MBTL1 | |
| SCHEMBL18566486 | 0.74 | PDE3B (0.41) | GABRA1GABRB2LMNASMN1; SMN2L3MBTL1 | |
| Hydrochloric Acid SCHEMBL28470006 | 0.73 | PDE3B (0.41) | GABRA1GABRB2LMNASMN1; SMN2L3MBTL1 | |
| SCHEMBL242311 | 0.71 | GABRA1 (0.41) | GABRA1GABRB2LMNASMN1; SMN2L3MBTL1 | |
| SCHEMBL17778287 | 0.70 | DPP4 (0.40) | GABRA1GABRB2LMNASMN1; SMN2L3MBTL1 | |
| Ammonia Solution, Strong SCHEMBL25385979 | 0.69 | GABRA1 (0.39) | GABRA1GABRB2LMNASMN1; SMN2L3MBTL1 | |
| SCHEMBL5786722 | 0.69 | GABRA1 (0.39) | GABRA1GABRB2LMNASMN1; SMN2L3MBTL1 | |
| Hydrochloric Acid SCHEMBL28665184 | 0.68 | GABRA1 (0.38) | GABRA1GABRB2LMNASMN1; SMN2L3MBTL1 | |
| Formamide SCHEMBL10696206 | 0.67 | ALDH1A1 (0.35) | GABRA1GABRB2LMNASMN1; SMN2L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1506175-A1 | N-SUBSTITUTED TRICYCLIC 3-AMINOPYRAZOLES AS PDGF RECEPTOR INHIBITORS | JANSSEN PHARMACEUTICA N.V. (BE) | 2005-02-16 | — | — | EP | disclosed |
| WO-2003097609-A1 | N-SUBSTITUTED TRICYCLIC 3-AMINOPYRAZOLES AS PDFG RECEPTOR INHIBITORS | JANSSEN PHARMACEUTICA N.V. (BE) | 2003-11-27 | — | — | WO | disclosed |
| EP-1341893-A1 | ENZYMATIC DETERGENT COMPOSITIONS | UNILEVER N.V. (NL) | 2003-09-10 | — | — | EP | disclosed |
| WO-2002048307-A1 | ENZYMATIC DETERGENT COMPOSITIONS | UNILEVER N.V. (NL) | 2002-06-20 | — | — | WO | disclosed |
| US-20020013246-A1 | Composition and method for bleaching laundry fabrics | UNILEVER HOME & PERSONAL CARE USA, DIVISION OF CONOPCO, INC. | 2002-01-31 | — | — | US | disclosed |
| EP-1109884-A1 | COMPOSITION AND METHOD FOR BLEACHING A SUBSTRATE | UNILEVER PLC (GB) | 2001-06-27 | — | — | EP | disclosed |
| WO-2000060043-A1 | COMPOSITION AND METHOD FOR BLEACHING A SUBSTRATE | UNILEVER PLC (GB) | 2000-10-12 | — | — | WO | disclosed |
| WO-2000012667-A1 | COMPOSITION AND METHOD FOR BLEACHING A SUBSTRATE | UNILEVER PLC (GB) | 2000-03-09 | — | — | WO | disclosed |