Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | PARP1 | P09874 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | GPR119 | Q8TDV5 | 5/20 | 0.46 |
| ▸ | ATM | Q13315 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | CFTR | P13569 | 1/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6993097 | 0.82 | GPR119 (0.51) | KMT2AGPR119 | |
| SCHEMBL2423448 | 0.80 | FAAH (0.52) | GPR119 | |
| SCHEMBL2423946 | 0.79 | HRH4 (0.51) | POLBSMN1; SMN2HTT | |
| SCHEMBL5234761 | 0.77 | KIT (0.47) | POLBGPR119 | |
| SCHEMBL30636902 | 0.77 | HTT (0.50) | PARP1KMT2ASMN1; SMN2HTT | |
| SCHEMBL18123360 | 0.77 | POLB (0.65) | POLBPARP1MEN1KMT2AGPR119 | |
| SCHEMBL948255 | 0.76 | GPR119 (0.53) | POLBGPR119HTT | |
| SCHEMBL2424622 | 0.76 | HTT (0.49) | KMT2ASMN1; SMN2USP2HTT | |
| SCHEMBL22468956 | 0.76 | ALDH1A1 (0.54) | MEN1KMT2AGPR119HTT | |
| SCHEMBL13741691 | 0.75 | HTT (0.44) | SMN1; SMN2HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1539178-A2 | PROTEASE INHIBITORS | SmithKline Beecham Corporation (US) | 2005-06-15 | — | — | EP | disclosed |
| WO-2004017911-A2 | PROTEASE INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 2004-03-04 | — | — | WO | disclosed |