Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | EGFR | P00533 | 10/20 | 0.34 |
| ▸ | CDK1 | P06493 | 4/20 | 0.34 |
| ▸ | CDK5 | Q00535 | 2/20 | 0.34 |
| ▸ | CCNC | P24863 | 1/20 | 0.33 |
| ▸ | CDK8 | P49336 | 1/20 | 0.33 |
| ▸ | CCNT1 | O60563 | 2/20 | 0.33 |
| ▸ | CDK9 | P50750 | 2/20 | 0.33 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.33 |
| ▸ | CX3CR1 | P49238 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6204529 | 0.83 | CCNE2 (0.44) | CDK1CDK5 | |
| SCHEMBL6201142 | 0.82 | CDK1 (0.46) | CDK1CDK5CCNT1CDK9 | |
| SCHEMBL3445624 | 0.77 | EGFR (0.39) | LMNAHPGDSMN1; SMN2EGFRCCNC | |
| SCHEMBL3445625 | 0.77 | EGFR (0.39) | LMNAHPGDSMN1; SMN2EGFRCCNC | |
| SCHEMBL6203326 | 0.77 | CDK2 (0.38) | EGFRCDK1CDK5CCNT1CDK9 | |
| SCHEMBL3445577 | 0.76 | CDK5 (0.39) | LMNAHPGDSMN1; SMN2EGFRCDK1 | |
| SCHEMBL3445318 | 0.76 | CDK5 (0.39) | LMNAHPGDSMN1; SMN2EGFRCDK1 | |
| SCHEMBL6203534 | 0.76 | CCNE2 (0.46) | CDK1 | |
| SCHEMBL6205187 | 0.76 | HTR2C (0.42) | CDK1CDK5 | |
| SCHEMBL6203887 | 0.74 | LMNA (0.38) | LMNAHPGDSMN1; SMN2EGFRCDK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1539760-A2 | AZAPURINE DERIVATIVES | INSTITUTE OF EXPERIMENTAL BOTANY ASCR (CZ) | 2005-06-15 | — | — | EP | claimed |
| WO-2004018473-A2 | AZAPURINE DERIVATIVES | INSTITUTE OF EXPERIMENTAL BOTANY ASCR (CZ) | 2004-03-04 | — | — | WO | claimed |
| EP-1539760-A2 | AZAPURINE DERIVATIVES | INSTITUTE OF EXPERIMENTAL BOTANY ASCR (CZ) | 2005-06-15 | — | — | EP | disclosed |
| WO-2004018473-A2 | AZAPURINE DERIVATIVES | INSTITUTE OF EXPERIMENTAL BOTANY ASCR (CZ) | 2004-03-04 | — | — | WO | disclosed |