SCHEMBL29007489

SCHEMBL29007489

COc1cccc(C(=O)CCc2ccccc2OC)c1

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GAA P10253 1/20 0.64
HPGD P15428 1/20 0.64
CTNNB1 P35222 2/20 0.55
WNT3A P56704 2/20 0.55
DRD4 P21917 3/20 0.55
DRD2 P14416 1/20 0.55
TDP1 Q9NUW8 2/20 0.54
LMNA P02545 1/20 0.54
MAPK1 P28482 1/20 0.54
HTT P42858 1/20 0.54
L3MBTL1 Q9Y468 1/20 0.54
NPC1 O15118 1/20 0.53
PKM P14618 1/20 0.53
RAB9A P51151 1/20 0.53
CES2 O00748 1/20 0.53
CES1 P23141 1/20 0.53
HSD11B1 P28845 2/20 0.52
ABCB1 P08183 1/20 0.51
ALDH1A1 P00352 1/20 0.51
MAPT P10636 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7188215 0.89 KMT2A (0.56) GAAHPGDCTNNB1WNT3ADRD4
SCHEMBL29007473 0.87 CTNNB1 (0.64) GAAHPGDCTNNB1WNT3AHTT
SCHEMBL6204029 0.86 NPC1 (0.55) HTTL3MBTL1NPC1PKMRAB9A
SCHEMBL8853339 0.84 NPC1 (0.65) TDP1HTTL3MBTL1NPC1PKM
SCHEMBL7195034 0.83 ALDH1A1 (0.52) GAAHPGDCTNNB1WNT3ADRD4
SCHEMBL7192539 0.82 CTNNB1 (0.52) GAAHPGDCTNNB1WNT3ADRD4
SCHEMBL8269548 0.82 HSD11B1 (0.64) HPGDCTNNB1WNT3ATDP1LMNA
SCHEMBL7190492 0.81 HSD17B10 (0.59) HPGDLMNAL3MBTL1NPC1PKM
SCHEMBL7166019 0.81 RAB9A (0.69) GAACTNNB1WNT3ATDP1LMNA
SCHEMBL15988793 0.79 CTNNB1 (0.74) GAACTNNB1WNT3ALMNANPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116199597-A Substituted phenyl diazonium salt and application thereof in catalytic preparation of 3-substituted indole compounds 盐城利民农化有限公司 2023-06-02 CN claimed