Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 15/20 | 0.39 |
| ▸ | CTSL | P07711 | 15/20 | 0.39 |
| ▸ | CTSS | P25774 | 14/20 | 0.39 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.33 |
| ▸ | HCRTR1 | O43613 | 2/20 | 0.33 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.33 |
| ▸ | CTSB | P07858 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6214223 | 0.82 | CTSK (0.56) | CTSKCTSLCTSSUSP30 | |
| SCHEMBL6262177 | 0.80 | CTSK (0.46) | CTSKCTSLCTSSCTSB | |
| SCHEMBL7015499 | 0.77 | CTSK (0.39) | CTSKCTSLCTSSUSP30CTSB | |
| SCHEMBL6073055 | 0.73 | CTSL (0.42) | CTSKCTSLCTSSUSP30CTSB | |
| SCHEMBL5983414 | 0.73 | CTSK (0.70) | CTSKCTSLCTSSCTSB | |
| SCHEMBL6072616 | 0.72 | CTSK (0.40) | CTSKCTSLCTSSUSP30CTSB | |
| SCHEMBL7006137 | 0.72 | CTSL (0.39) | CTSKCTSLCTSSUSP30CTSB | |
| SCHEMBL7010659 | 0.71 | CTSK (0.34) | CTSKCTSLCTSS | |
| SCHEMBL6072667 | 0.71 | CTSK (0.41) | CTSKCTSLCTSSUSP30CTSB | |
| SCHEMBL8339254 | 0.71 | MAPK11 (0.49) | CAPN1HCRTR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1539178-A2 | PROTEASE INHIBITORS | SmithKline Beecham Corporation (US) | 2005-06-15 | — | — | EP | disclosed |
| WO-2004017911-A2 | PROTEASE INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 2004-03-04 | — | — | WO | disclosed |